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Created page with '===Murine Parainfluenza - 1 (Sendai Virus)=== *Endemic in many '''mouse''' colonies *Most mice show no symptoms due to maternal antibodies *But minor respiratory lesions may …'
===Murine Parainfluenza - 1 ([[Sendai Virus]])===
*Endemic in many '''mouse''' colonies
*Most mice show no symptoms due to maternal antibodies
*But minor respiratory lesions may invalidate carcinogenic or toxicological studies
*Immunological studies also confused due to virus activating [[Lymphocytes - WikiBlood#Natural Killer (NK) Cells|NK cells]] via high circulating [[Innate Immune System - WikiBlood#Interferons|IF]] 3-4 days post-infection
*Control achieved by:
**Purchasing '''specific pathogen free (SPF)''' mice
**Kill whole colony in an outbreak -> disinfection -> formalin fumigation
[[Category:Paramyxovirinae]][[Category:Rodents]]
*Endemic in many '''mouse''' colonies
*Most mice show no symptoms due to maternal antibodies
*But minor respiratory lesions may invalidate carcinogenic or toxicological studies
*Immunological studies also confused due to virus activating [[Lymphocytes - WikiBlood#Natural Killer (NK) Cells|NK cells]] via high circulating [[Innate Immune System - WikiBlood#Interferons|IF]] 3-4 days post-infection
*Control achieved by:
**Purchasing '''specific pathogen free (SPF)''' mice
**Kill whole colony in an outbreak -> disinfection -> formalin fumigation
[[Category:Paramyxovirinae]][[Category:Rodents]]