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*"True ulcer" occurs when connective tissue under epithelium is exposed i.e. stratum germinativum is breached and then lesion takes much longer to heal.
 
*"True ulcer" occurs when connective tissue under epithelium is exposed i.e. stratum germinativum is breached and then lesion takes much longer to heal.
 
===[[Bovine Virus Diarrhoea Virus]]===
 
===[[Bovine Virus Diarrhoea Virus]]===
*'''Mucosal Disease''': erosive condition produces small multiple, cleanly punched out lesion in mouth
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*[[Neutrophils - WikiBlood|Neutrophils]] invade the ulcer and if bacterial colonisation occurs, further excavation follows. Either:
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::#This lesion develops a granular base and becomes diphtheritic.
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::#If bacterial colonisation does not take place, healing occurs within fourteen days.
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*Seen in most parts of mouth (or maybe on muzzle) e.g. dental pad, [[Cheeks - Anatomy & Physiology|cheeks]], sides of [[Oral Cavity - Tongue - Anatomy & Physiology|tongue]]
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*Lesions extend throughout gut with particularly big ulcers in small intestine over [[Peyer's Patches - Anatomy & Physiology|Peyers patches]]. Necrosis occurs in lymph nodes and [[Spleen - Anatomy & Physiology|spleen]]
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====<span id="BVDHistology">Histology</span>====
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*No vesicular stage, prickle cells die off from surface resulting in layer of necrotic debris over epithelial layer
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*Infection penetrates inward through stratum germinativum.
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*Epithelium does not recover as animal does not recover
      
===[[Malignant Catarrhal Fever Virus]]===
 
===[[Malignant Catarrhal Fever Virus]]===
 
[[Category:Oral Cavity and Gingiva - Pathology]]
 
[[Category:Oral Cavity and Gingiva - Pathology]]
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