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| **Induces virus-neutralizing antibodies | | **Induces virus-neutralizing antibodies |
| *Vaccination DOES NOT render meat harmful to consumers, but does affect when it can be exported | | *Vaccination DOES NOT render meat harmful to consumers, but does affect when it can be exported |
| + | |
| + | ====Pathology==== |
| + | =====Gross===== |
| + | #Initially - hyperaemia of mucosa (e.g. catarrhal inflammation) then within 12 hours produces fluid filled vesicles on dorsum of [[Oral Cavity - Tongue - Anatomy & Physiology|tongue]], may be other places |
| + | #Small vesicle coalesce to produce big ones -i.e. Bullae |
| + | #Very quickly rupture; epithelium appears dirty grey in colour because of necrosis - sloughed skin, very good for diagnosis |
| + | #Leave painful, hyperaemic epithelium |
| + | #Looks like "ulcer "with ragged edge but not a true ulcer as stratum germinativum retained and will rapidly heal completely in about 2 weeks unless becomes secondarily infected |
| + | |
| + | =====Microscopic lesions===== |
| + | *Degeneration of prickle cells |
| + | *Cells "balloon" as fill with fluid and then die to produce vesicle containing straw coloured or clear fluid |
| + | |
| | | |
| ====For more information==== | | ====For more information==== |
| [http://www.defra.gov.uk/footandmouth/ DEFRA] | | [http://www.defra.gov.uk/footandmouth/ DEFRA] |
| [[Category:Apthoviruses]][[Category:Cattle]][[Category:Sheep]][[Category:Goat]][[Category:Pig]] | | [[Category:Apthoviruses]][[Category:Cattle]][[Category:Sheep]][[Category:Goat]][[Category:Pig]] |