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Created page with '==Granulomatous Inflammation== ===Traumatic Reticulitis=== ===Mucormycosis=== * ''Mucor'', a fungi, invades the rumen wall, e.g. afte…'
==Granulomatous Inflammation==

===[[Traumatic Reticulitis]]===



===Mucormycosis===
* ''Mucor'', a fungi, invades the [[The Rumen - Anatomy & Physiology|rumen]] wall, e.g. after damage caused by [[Rumenal Acidosis|rumenal acidosis]].
* Produces chronic ongoing granulomatous rumenitis.
* Difficult to diagnose in life.
* May produce pain and poor growth
* Infective process may penetrate wall and produce peritonitis.

====Pathology====

=====Gross=====

* Thickening and ulceration of mucosal surface of [[The Rumen - Anatomy & Physiology|rumen]].
** Feels like thick leather.
*[[The Rumen - Anatomy & Physiology|Rumen]] wall becomes fibrosed.

=====Histological=====

* Classical granulomatous inflammation
** May have giant cells in addition to sheets of [[Macrophages - WikiBlood|macrophages]].
* Can visualise fungal hyphae in tissue using special stains (PAS),
** Often grow along blood vessels.
*** May cause thrombosis of small blood vessels, leading to further necrosis (infarction) of [[The Rumen - Anatomy & Physiology|rumen]] wall.

==Neutrophilic Inflammation==

===Rumenitis===

* Opportunistic pathogens take advantage of acidotic lesions and other disturbances of rumen flora.
** e.g. ''F. necrophorum'', fungi
** Infection with ''Mucor'' gives [[Mucormycosis|mucormycosis]]- chronic ongoing granulomatous rumenitis.
** Also agents which cause lesions in other areas of tract e.g. BVDV, actinobacillosis.

====Pathology====

=====Gross=====

* Multiple, dark red areas of swollen papillae, mainly in ventral sac and pillars.

=====Histological=====

* Coagulative necrosis of papillae
* Marked neutrophil infiltrate
* Serofibrinous exudate
* Thromboembolic spread to form areas of coagulative necrosis and abscesses in [[Liver - Anatomy & Physiology|liver]].
[[Category:Forestomach_-_Pathology]]
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