* Many bacteria produce toxins that are often responsible for clinical effects.
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** e.g. [[Oedema Disease|oedema disease]] due to [[Escherichia coli|''E. Coli'']].
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*** Toxin is produced in the gut but is absorbed into the circulation to take effect elsewhere.
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* Systemic effects of these toxins may kill the animal.
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* Systemic toxicosis derived from organisms in the alimentary tract is also seen with the [[:Category:Clostridium species|''Clostridia'']] group of bacteria.