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| | ==[[Liver Failure]]== | | ==[[Liver Failure]]== |
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| | + | ===Syndromes in liver failure=== |
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| | [[Icterus]] | | [[Icterus]] |
| − | ===Syndromes in liver failure===
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| | + | [[Photosensitisation]] |
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| − | ====[[Photosensitisation]]====
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| | + | [[Hepatic Encephalopathy]] |
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| − | ====Hepatic Encephalopathy====
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| − | =====Clinical=====
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| − | *non-specific neurological signs (attributed to the retention of ammonia and gamma aminobutyric acid in [[Liver - Anatomy & Physiology|liver]] failure and their effects on the brain)
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| − | **dullness
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| − | **apparent unawareness of surroundings
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| − | **pointless or compulsive movements
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| − | **mania
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| − | **generalised convulsions
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| − | NB: usually soon followed by death
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| − | =====Microscopically=====
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| − | *lesions in the brain vary in expression
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| − | **most species may show myelin degeneration consisting of vacuoles between the grey and white matter
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| − | **the horse may show very little visible neural changes, perhaps an increase in astrocytes
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| − | =====Causes=====
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| − | ::[[Liver Developmental - Pathology#Portosystemic shunt|Portosystemic Shunting]]
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| − | ::Chronic [[Liver - Anatomy & Physiology|liver]] damage
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| − | *due to ingestion of toxic compounds over a long period of time
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| − | *E.g. [[Liver Toxic - Pathology#ragwort|ragwort]]
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| | ====Bleeding Tendencies==== | | ====Bleeding Tendencies==== |