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==Liver response to injury==
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==[[Liver response to injury]]==
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*Again, the [[Liver - Anatomy & Physiology|liver]] is liable to injury from many causes and this is especially the case for a number of reasons
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**''position''
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***the [[Liver - Anatomy & Physiology|liver]] acts as a second barrier between the non-sterile intestinal contents and the systemic circulation
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***is exposed to viruses, bacterial toxins, and poisons absorbed from the portal blood
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**''energy requirements''
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***relatively enormous amounts of energy are utilised by [[Liver - Anatomy & Physiology|liver]] cells and this renders them more vulnerable to anoxia and toxaemia
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**''detoxification''
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***the [[Liver - Anatomy & Physiology|liver]] acts as a detoxifying organ and may suffer in consequence
===Necrosis===
===Necrosis===