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| | ***Serovar ''bratislava'' causes abortion and infertility in dogs, which may be the maintenance host | | ***Serovar ''bratislava'' causes abortion and infertility in dogs, which may be the maintenance host |
| | ***Infections uncommon in cats | | ***Infections uncommon in cats |
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| | + | *''Leptospirosis icterohaemorrhagica'' - a septicaemic disease which affects the [[Liver - Anatomy & Physiology|liver]] |
| | + | *puppies |
| | + | *Leptospirosis is an important spirochaetal group of diseases causing disease in animals and humans (zoonotic) |
| | + | *Transmission |
| | + | **via urine of affected animals |
| | + | **organisms can remain viable for weeks in damp conditions |
| | + | *method of action |
| | + | **cause anaemia via intravascular haemolysis |
| | + | =====Clinical===== |
| | + | *fever |
| | + | *dehydration |
| | + | *haemorrhaging from the mucous membranes of the body |
| | + | =====Diagnosis===== |
| | + | *dark field microscopy on fresh urine is best |
| | + | =====Gross===== |
| | + | *widespread hameorrhages |
| | + | *icterus |
| | + | *pale foci in the [[Liver - Anatomy & Physiology|liver]] (not always a constant finding) |
| | + | *subcapsular and cortical renal haemorrhages |
| | + | =====Microscopically===== |
| | + | *foci of necrosis |
| | + | *dissociation of hepatocytes form each other (similar to post mortem change) |
| | + | *substantial haemosiderin in the Kuppfer cells (from the haemolysis) |
| | + | *need to use a silver stain or immunofluorescence to demonstrate the organisms in tissues |
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| | [[Category:Leptospiraceae]][[Category:Cat]][[Category:Dog]] | | [[Category:Leptospiraceae]][[Category:Cat]][[Category:Dog]] |
| | + | [[Category:Hepatitis,_Bacterial]] |