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***Serovar ''bratislava'' causes abortion and infertility in dogs, which may be the maintenance host
 
***Serovar ''bratislava'' causes abortion and infertility in dogs, which may be the maintenance host
 
***Infections uncommon in cats
 
***Infections uncommon in cats
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*''Leptospirosis icterohaemorrhagica'' - a septicaemic disease which affects the [[Liver - Anatomy & Physiology|liver]]
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*puppies
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*Leptospirosis is an important spirochaetal group of diseases causing disease in animals and humans (zoonotic)
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*Transmission
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**via urine of affected animals
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**organisms can remain viable for weeks in damp conditions
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*method of action
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**cause anaemia via intravascular haemolysis
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=====Clinical=====
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*fever
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*dehydration
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*haemorrhaging from the mucous membranes of the body
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=====Diagnosis=====
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*dark field microscopy on fresh urine is best
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=====Gross=====
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*widespread hameorrhages
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*icterus
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*pale foci in the [[Liver - Anatomy & Physiology|liver]] (not always a constant finding)
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*subcapsular and cortical renal haemorrhages
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=====Microscopically=====
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*foci of necrosis
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*dissociation of hepatocytes form each other (similar to post mortem change)
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*substantial haemosiderin in the Kuppfer cells (from the haemolysis)
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*need to use a silver stain or immunofluorescence to demonstrate the organisms in tissues
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[[Category:Leptospiraceae]][[Category:Cat]][[Category:Dog]]
 
[[Category:Leptospiraceae]][[Category:Cat]][[Category:Dog]]
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[[Category:Hepatitis,_Bacterial]]
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