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==Signalment and Description==
==Signalment and Description==
===Hepatocellular Tumours ([[Liver Proliferative - Pathology #Hepatocytic|Hepatocellular carcinomas]] (HCC) and [[Liver Proliferative - Pathology #Hepatocytic|Hepatomas]])===
===Hepatocellular Tumours ([[Carcinoma#Hepatocytic|Hepatocellular carcinomas]] (HCC) and [[Adenoma#Hepatocytic|Hepatomas]])===
* HCC occurs more frequently in dogs and hepatomas more commonly in cats. They are the most common primary liver tumour in dogs and the second most common in cats.
* HCC occurs more frequently in dogs and hepatomas more commonly in cats. They are the most common primary liver tumour in dogs and the second most common in cats.
* Male dogs over 10 years old are the most frequently affected by HCC and Miniature schnauzers may have a breed predisposition.
* Male dogs over 10 years old are the most frequently affected by HCC and Miniature schnauzers may have a breed predisposition.
* Metastatic rate for dogs with massive HCC: 0-37%
* Metastatic rate for dogs with massive HCC: 0-37%
* Metastatic rate for dogs with nodular and diffuse HCC: 93-100%
* Metastatic rate for dogs with nodular and diffuse HCC: 93-100%
* [[Liver Proliferative - Pathology #Hepatocytic|Hepatomas]]) are usually incidental findings and non-significant
* [[Adenoma#Hepatocytic|Hepatomas]]) are usually incidental findings and non-significant
===Cholangiocellular Tumours (Bile duct carcinomas and adenomas)===
===Cholangiocellular Tumours (Bile duct carcinomas and adenomas)===
* Primary tumours are aggressive and often affect more than one liver lobe and metastasise most frequently to the regional lymph nodes, the lungs and peritoneum.
* Primary tumours are aggressive and often affect more than one liver lobe and metastasise most frequently to the regional lymph nodes, the lungs and peritoneum.
===Sarcomas ([[Liver Proliferative - Pathology #Haemangiosarcoma|Haemangiosarcoma]] (HSA), Leiomyosarcoma, Fibrosarcoma)===
===Sarcomas ([[Haemangiosarcoma|Haemangiosarcoma]] (HSA), Leiomyosarcoma, Fibrosarcoma)===
* HSA is the most common hepatic sarcoma in cats
* HSA is the most common hepatic sarcoma in cats
* Leiomyosarcoma is the most common hepatic sarcoma in dogs
* Leiomyosarcoma is the most common hepatic sarcoma in dogs
==Treatment==
==Treatment==
===Surgery===
===Surgery===
Surgical excision is advised for hepatic adenomas, bile duct adenomas and massive [[Liver Proliferative - Pathology #Hepatocytic|hepatocellular carcinomas]]. Nodulectomy or lobectomy can be used for focal tumours of one or more lobes. Diffuse tumours and widespread nodular disease carry a worse prognosis.
Surgical excision is advised for hepatic adenomas, bile duct adenomas and massive [[Carcinoma#Hepatocytic|hepatocellular carcinomas]]. Nodulectomy or lobectomy can be used for focal tumours of one or more lobes. Diffuse tumours and widespread nodular disease carry a worse prognosis.
===Chemotherapy===
===Chemotherapy===
Not currently recommended for primary hepatic neoplasia. Some metastatic sarcomas, for example [[Liver Proliferative - Pathology #Haemangiosarcoma|haemangiosarcomas]], may show some response.
Not currently recommended for primary hepatic neoplasia. Some metastatic sarcomas, for example [[Haemangiosarcoma|haemangiosarcomas]], may show some response.
===Radiotherapy===
===Radiotherapy===
==Prognosis==
==Prognosis==
The mean survival time for massive [[Liver Proliferative - Pathology #Hepatocytic|hepatocellular carcinomas]] following surgery is approximately 1 year. Otherwise the prognosis is poor for other malignant and metastatic tumours. If successfully excised the prognosis for benign tumours is good.
The mean survival time for massive [[Carcinoma#Hepatocytic|hepatocellular carcinomas]] following surgery is approximately 1 year. Otherwise the prognosis is poor for other malignant and metastatic tumours. If successfully excised the prognosis for benign tumours is good.