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Category:Pancreas - Developmental Pathology (view source)
Revision as of 12:30, 9 June 2010
, 12:30, 9 June 2010Created page with '==Pancreatic hypoplasia== [http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=1546 Image of pancreatic hypoplasia in a dog from Cornell Veterinary Medicine] *Occurs in calve…'
==Pancreatic hypoplasia==
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=1546 Image of pancreatic hypoplasia in a dog from Cornell Veterinary Medicine]
*Occurs in calves, dogs (German Shepherd Dogs are the prevalent breed) and cats
*Endocrine part of the pancreas seems unaffected
===Clinical signs===
*[[EPI|Exocrine pancreatic insufficiency]]
*Occurs at about one year of age
*Onset often preceded by another illness
===Gross appearance===
*Pot-bellied appearance on external view
*Intestines are distended by bulky fatty ingesta
*Lack of fat in the mesentery and rest of the abdomen
*The pancreas appears extremely thin and almost lace-like, is sparse and pink, easily visible due to lack of fat
*The hypoplastic pancreas may be inconspicuous at laparotomy or post mortem examination owing to its small size
===Microscopic appearance===
*Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the [[Pancreas - Anatomy & Physiology|pancreas]] is normal at birth but undergoes progressive regression - [[Pancreas Degenerative - Pathology#Juvenile pancreatic atrophy|juvenile atrophy]]
*Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells
==Ductal abnormalities==
*Congenital stenosis
*Cystic dilation
**[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=16178 Image of chronic pancreatitis with cystic ducts in a horse from Cornell Veterinary Medicine]
**Occurs mostly in cats and occasionally in lambs
**The cystic nature of the ducts can be accompanied by cysts in [[Liver - Anatomy & Physiology|liver]] and [[Urinary System - Anatomy & Physiology#Upper Urinary Tract|kidneys]] - polycystic
==Ectopic pancreatic tissue==
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=1331 Image of ectopic pancreas on duodenum of a dog from Cornell Veterinary Medicine]
*Sometimes small pieces of pancreatic tissue are seen in diverse places like the submucosa and muscle of nearby [[Alimentary - Anatomy & Physiology|alimentary tract]], [[Liver - Anatomy & Physiology|liver]], [[Gall Bladder - Anatomy & Physiology|gall bladder]], [[Spleen - Anatomy & Physiology|spleen]] and mesentery
*Occurs in dog and cat
==Pancreatic calculi==
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=7287 Image of pancreatic calculi and fibrosis in a cow from Cornell Veterinary Medicine]
*Pancreolithiasis occurs uncommonly in cattle, rarely in other species
*Slightly more common in cattle >4 years old
*Usually an incidental finding
*Usually calcium carbonate and calcium phosphate
*May be a consequence of inflammation, such as caused by [[Pancreas Parasitic - Pathology|flukes]]
==Stromal fat cell infiltration==
*Occurs occasionally
*Fat cell infiltration into interstitial tisue
*Function of the pancreas is unaffected
*Especially in obese cats and pigs[[Category:Pancreas - Pathology]]
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=1546 Image of pancreatic hypoplasia in a dog from Cornell Veterinary Medicine]
*Occurs in calves, dogs (German Shepherd Dogs are the prevalent breed) and cats
*Endocrine part of the pancreas seems unaffected
===Clinical signs===
*[[EPI|Exocrine pancreatic insufficiency]]
*Occurs at about one year of age
*Onset often preceded by another illness
===Gross appearance===
*Pot-bellied appearance on external view
*Intestines are distended by bulky fatty ingesta
*Lack of fat in the mesentery and rest of the abdomen
*The pancreas appears extremely thin and almost lace-like, is sparse and pink, easily visible due to lack of fat
*The hypoplastic pancreas may be inconspicuous at laparotomy or post mortem examination owing to its small size
===Microscopic appearance===
*Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the [[Pancreas - Anatomy & Physiology|pancreas]] is normal at birth but undergoes progressive regression - [[Pancreas Degenerative - Pathology#Juvenile pancreatic atrophy|juvenile atrophy]]
*Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells
==Ductal abnormalities==
*Congenital stenosis
*Cystic dilation
**[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=16178 Image of chronic pancreatitis with cystic ducts in a horse from Cornell Veterinary Medicine]
**Occurs mostly in cats and occasionally in lambs
**The cystic nature of the ducts can be accompanied by cysts in [[Liver - Anatomy & Physiology|liver]] and [[Urinary System - Anatomy & Physiology#Upper Urinary Tract|kidneys]] - polycystic
==Ectopic pancreatic tissue==
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=1331 Image of ectopic pancreas on duodenum of a dog from Cornell Veterinary Medicine]
*Sometimes small pieces of pancreatic tissue are seen in diverse places like the submucosa and muscle of nearby [[Alimentary - Anatomy & Physiology|alimentary tract]], [[Liver - Anatomy & Physiology|liver]], [[Gall Bladder - Anatomy & Physiology|gall bladder]], [[Spleen - Anatomy & Physiology|spleen]] and mesentery
*Occurs in dog and cat
==Pancreatic calculi==
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=7287 Image of pancreatic calculi and fibrosis in a cow from Cornell Veterinary Medicine]
*Pancreolithiasis occurs uncommonly in cattle, rarely in other species
*Slightly more common in cattle >4 years old
*Usually an incidental finding
*Usually calcium carbonate and calcium phosphate
*May be a consequence of inflammation, such as caused by [[Pancreas Parasitic - Pathology|flukes]]
==Stromal fat cell infiltration==
*Occurs occasionally
*Fat cell infiltration into interstitial tisue
*Function of the pancreas is unaffected
*Especially in obese cats and pigs[[Category:Pancreas - Pathology]]