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| − | ==Pancreatic hypoplasia== | + | {{frontpage |
| | + | |pagetitle =Pancreas - Developmental Pathology |
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| | + | <categorytree mode=pages>Pancreas - Developmental Pathology</categorytree> |
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| − | [http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=1546 Image of pancreatic hypoplasia in a dog from Cornell Veterinary Medicine]
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| − | *Occurs in calves, dogs (German Shepherd Dogs are the prevalent breed) and cats
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| − | *Endocrine part of the pancreas seems unaffected
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| − | ===Clinical signs===
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| − | *[[EPI|Exocrine pancreatic insufficiency]]
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| − | *Occurs at about one year of age
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| − | *Onset often preceded by another illness
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| − | | + | [[Category:Pancreas - Pathology]] |
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| − | ===Gross appearance===
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| − | *Pot-bellied appearance on external view
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| − | *Intestines are distended by bulky fatty ingesta
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| − | *Lack of fat in the mesentery and rest of the abdomen
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| − | *The pancreas appears extremely thin and almost lace-like, is sparse and pink, easily visible due to lack of fat
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| − | *The hypoplastic pancreas may be inconspicuous at laparotomy or post mortem examination owing to its small size
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| − | ===Microscopic appearance===
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| − | *Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the [[Pancreas - Anatomy & Physiology|pancreas]] is normal at birth but undergoes progressive regression - [[Pancreas Degenerative - Pathology#Juvenile pancreatic atrophy|juvenile atrophy]]
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| − | *Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells
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| − | ==Ductal abnormalities==
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| − | *Congenital stenosis
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| − | *Cystic dilation
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| − | **[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=16178 Image of chronic pancreatitis with cystic ducts in a horse from Cornell Veterinary Medicine]
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| − | **Occurs mostly in cats and occasionally in lambs
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| − | **The cystic nature of the ducts can be accompanied by cysts in [[Liver - Anatomy & Physiology|liver]] and [[Urinary System - Anatomy & Physiology#Upper Urinary Tract|kidneys]] - polycystic
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| − | ==Ectopic pancreatic tissue==
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| − | [http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=1331 Image of ectopic pancreas on duodenum of a dog from Cornell Veterinary Medicine]
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| − | *Sometimes small pieces of pancreatic tissue are seen in diverse places like the submucosa and muscle of nearby [[Alimentary - Anatomy & Physiology|alimentary tract]], [[Liver - Anatomy & Physiology|liver]], [[Gall Bladder - Anatomy & Physiology|gall bladder]], [[Spleen - Anatomy & Physiology|spleen]] and mesentery
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| − | *Occurs in dog and cat
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| − | ==Pancreatic calculi==
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| − | [http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=7287 Image of pancreatic calculi and fibrosis in a cow from Cornell Veterinary Medicine]
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| − | *Pancreolithiasis occurs uncommonly in cattle, rarely in other species
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| − | *Slightly more common in cattle >4 years old
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| − | *Usually an incidental finding
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| − | *Usually calcium carbonate and calcium phosphate
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| − | *May be a consequence of inflammation, such as caused by [[Pancreas Parasitic - Pathology|flukes]]
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| − | ==Stromal fat cell infiltration==
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| − | *Occurs occasionally
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| − | *Fat cell infiltration into interstitial tisue
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| − | *Function of the pancreas is unaffected
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| − | *Especially in obese cats and pigs[[Category:Pancreas - Pathology]]
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