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Created page with '[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=1546 Image of pancreatic hypoplasia in a dog from Cornell Veterinary Medicine] *Occurs in calves, dogs (German Shepherd Do…'
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=1546 Image of pancreatic hypoplasia in a dog from Cornell Veterinary Medicine]
*Occurs in calves, dogs (German Shepherd Dogs are the prevalent breed) and cats
*Endocrine part of the pancreas seems unaffected
===Clinical signs===
*[[EPI|Exocrine pancreatic insufficiency]]
*Occurs at about one year of age
*Onset often preceded by another illness
===Gross appearance===
*Pot-bellied appearance on external view
*Intestines are distended by bulky fatty ingesta
*Lack of fat in the mesentery and rest of the abdomen
*The pancreas appears extremely thin and almost lace-like, is sparse and pink, easily visible due to lack of fat
*The hypoplastic pancreas may be inconspicuous at laparotomy or post mortem examination owing to its small size
===Microscopic appearance===
*Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the [[Pancreas - Anatomy & Physiology|pancreas]] is normal at birth but undergoes progressive regression - [[Pancreas Degenerative - Pathology#Juvenile pancreatic atrophy|juvenile atrophy]]
*Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells
[[Category:Pancreas - Developmental Pathology]][[Category:Cattle]][[Category:Cat]][[Category:Dog]]
*Occurs in calves, dogs (German Shepherd Dogs are the prevalent breed) and cats
*Endocrine part of the pancreas seems unaffected
===Clinical signs===
*[[EPI|Exocrine pancreatic insufficiency]]
*Occurs at about one year of age
*Onset often preceded by another illness
===Gross appearance===
*Pot-bellied appearance on external view
*Intestines are distended by bulky fatty ingesta
*Lack of fat in the mesentery and rest of the abdomen
*The pancreas appears extremely thin and almost lace-like, is sparse and pink, easily visible due to lack of fat
*The hypoplastic pancreas may be inconspicuous at laparotomy or post mortem examination owing to its small size
===Microscopic appearance===
*Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the [[Pancreas - Anatomy & Physiology|pancreas]] is normal at birth but undergoes progressive regression - [[Pancreas Degenerative - Pathology#Juvenile pancreatic atrophy|juvenile atrophy]]
*Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells
[[Category:Pancreas - Developmental Pathology]][[Category:Cattle]][[Category:Cat]][[Category:Dog]]