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Category:Pancreas - Hyperplastic and Neoplastic Pathology (view source)
Revision as of 13:17, 9 June 2010
, 13:17, 9 June 2010Created page with '==Pancreas - Nodular Hyperplasia== ==Neoplasia== *Originates from the exocrine tissue or excretory ducts *Neoplasia of the '''[[Pancreas - Anatomy & Physiology#Endocrine|…'
==[[Pancreas - Nodular Hyperplasia]]==
==Neoplasia==
*Originates from the exocrine tissue or excretory ducts
*Neoplasia of the '''[[Pancreas - Anatomy & Physiology#Endocrine|Islet cells]]''' is rare but may cause hypoglycaemia due to overproduction of insulin
==Adenoma==
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=7754 Image of multifocal pancreatic adenoma in a dog from Cornell Veterinary Medicine]
*Very rare
*May be difficult to distinguish from nodular hyperplasia
*Single and larger nodules than normal [[Pancreas - Anatomy & Physiology|pancreas]]
==Carcinoma==
[[Image:Pancreatic carcinoma.jpg|right|thumb|100px|<small><center>Pancreatic carcinoma (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=11616 Image of haemorrhage and pancreatic carcinoma in a cat from Cornell Veterinary Medicine]
*In older dogs, more common in Airedale terriers, rare in cats, other species too
*Tend to arise centrally in the gland
*Highly invasive and infiltrative
*Metastases to the [[Liver - Anatomy & Physiology|liver]], visceral serosa, abdominal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]], [[Adrenal Glands - Anatomy & Physiology|adrenals]] etc.
*Similar to malignant ovarian tumours - implant on the [[Peritoneal cavity - Anatomy & Physiology|peritoneum]]
===Gross appearance===
[[Image:Pancreatic carcinoma histo.jpg|right|thumb|100px|<small><center>Pancreatic carcinoma (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
*Usually spherical nodules with adhesions to nearby structures
*Single or multiple, variable size
*Greyish or yellow fibrous tissue - firm on cutting
*May show internal necrosis and haemorrhage
*Some tumours may contain cysts wih mucinous content
*Adhesions may occur
===Microscopic appearance===
*May be well differentiated with normal acini and ducts
*Or diffuse sheet of undifferentiated cells
[[Category:Pancreas_-_Pathology]]
==Neoplasia==
*Originates from the exocrine tissue or excretory ducts
*Neoplasia of the '''[[Pancreas - Anatomy & Physiology#Endocrine|Islet cells]]''' is rare but may cause hypoglycaemia due to overproduction of insulin
==Adenoma==
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=7754 Image of multifocal pancreatic adenoma in a dog from Cornell Veterinary Medicine]
*Very rare
*May be difficult to distinguish from nodular hyperplasia
*Single and larger nodules than normal [[Pancreas - Anatomy & Physiology|pancreas]]
==Carcinoma==
[[Image:Pancreatic carcinoma.jpg|right|thumb|100px|<small><center>Pancreatic carcinoma (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
[http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=11616 Image of haemorrhage and pancreatic carcinoma in a cat from Cornell Veterinary Medicine]
*In older dogs, more common in Airedale terriers, rare in cats, other species too
*Tend to arise centrally in the gland
*Highly invasive and infiltrative
*Metastases to the [[Liver - Anatomy & Physiology|liver]], visceral serosa, abdominal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]], [[Adrenal Glands - Anatomy & Physiology|adrenals]] etc.
*Similar to malignant ovarian tumours - implant on the [[Peritoneal cavity - Anatomy & Physiology|peritoneum]]
===Gross appearance===
[[Image:Pancreatic carcinoma histo.jpg|right|thumb|100px|<small><center>Pancreatic carcinoma (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
*Usually spherical nodules with adhesions to nearby structures
*Single or multiple, variable size
*Greyish or yellow fibrous tissue - firm on cutting
*May show internal necrosis and haemorrhage
*Some tumours may contain cysts wih mucinous content
*Adhesions may occur
===Microscopic appearance===
*May be well differentiated with normal acini and ducts
*Or diffuse sheet of undifferentiated cells
[[Category:Pancreas_-_Pathology]]