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| ===Aetiology=== | | ===Aetiology=== |
| *Hypoplasia of [[Pancreas - Anatomy & Physiology#Endocrine|panceatic islets]] where [[Pancreas - Anatomy & Physiology|exocrine]] cells are functional | | *Hypoplasia of [[Pancreas - Anatomy & Physiology#Endocrine|panceatic islets]] where [[Pancreas - Anatomy & Physiology|exocrine]] cells are functional |
− | *Degeneration of the [[Pancreas - Anatomy & Physiology#Endocrine|islet]] cells occurs in [[Pancreatic Necrosis, Acute|acute pancreatic necrosis]] along with acinar tissue necrosis, atrophy occurs during [[Pancreatitis, Chronic Interstitial|chronic interstitial pancreatitis]] | + | *Degeneration of the [[Pancreas - Anatomy & Physiology#Endocrine|islet]] cells occurs in [[Pancreatic Necrosis, Acute|acute pancreatic necrosis]] along with acinar tissue necrosis, atrophy occurs during [[Pancreatitis|chronic interstitial pancreatitis]] |
| *Extensive neoplastic destruction may also contribute to [[Pancreas - Anatomy & Physiology#Endocrine|islet]] loss | | *Extensive neoplastic destruction may also contribute to [[Pancreas - Anatomy & Physiology#Endocrine|islet]] loss |
| *Causes [[DM|Diabetes mellitus]] (DM) | | *Causes [[DM|Diabetes mellitus]] (DM) |
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| **'''Amyloidosis''' of the [[Pancreas - Anatomy & Physiology#Endocrine|islets]] is sometimes observed and may be restricted to just them | | **'''Amyloidosis''' of the [[Pancreas - Anatomy & Physiology#Endocrine|islets]] is sometimes observed and may be restricted to just them |
| ***May result in signs of [[DM|DM]] or have no symptoms | | ***May result in signs of [[DM|DM]] or have no symptoms |
− | ***[[Degenerations and Infiltrations - Pathology#Vacuolar Degeneration|Hydropic (vacuolar) degeneration]] of beta cells | + | ***[[Hydropic Degeneration#Vacuolar Degeneration|Hydropic (vacuolar) degeneration]] of beta cells |
| ***Acumultion of glycogen within the cytoplasm | | ***Acumultion of glycogen within the cytoplasm |
| ***Develops in response to long-term overstimulation due to peripheral insulin resistance | | ***Develops in response to long-term overstimulation due to peripheral insulin resistance |
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| [[Category:Pancreas_-_Degenerative_Pathology]][[Category:Endocrine System - Pathology]] | | [[Category:Pancreas_-_Degenerative_Pathology]][[Category:Endocrine System - Pathology]] |
| + | [[Category:To_Do_-_Clinical]] |