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Endocrine Pancreas - Pathology (view source)

Revision as of 13:36, 9 June 2010

387 bytes removed ,  13:36, 9 June 2010
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==Neoplasia==
 
==Neoplasia==
 
[[Image:Islet cell tumour.jpg|right|thumb|100px|<small><center>Islet cell tumour (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
 
[[Image:Islet cell tumour.jpg|right|thumb|100px|<small><center>Islet cell tumour (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
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===Insulin secreting neoplasms===
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===[[Insulin Secreting Neoplasms]]===
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*Adenomas and carcinomas deerived from beta cells
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*Respond rapidly to iv glucose
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*Can be identified by immunocytochemical means
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*Dogs 5-12 years of age most commonly affected
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*Older cattle, associated with periodic convulsions
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====Clinical signs====
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*Hyperinsulinism
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*Hypoglycaemia - often episodic
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**Neurologic signs - stupor, confusion, coma, seizures, peripheral neuropathy may also develop
   
===Adenomas (insulinomas)===
 
===Adenomas (insulinomas)===
 
*Usually single, or less often multiple, small (1-3cm) spherical nodule, yellow to dark red,  in one or more lobes
 
*Usually single, or less often multiple, small (1-3cm) spherical nodule, yellow to dark red,  in one or more lobes
Bara
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