Changes

** Chiefly function to replace the various tissue macrophage populations

** Chiefly function to replace the various tissue macrophage populations

===[[Neutrophils - WikiBlood|Neutrophils]]===

===[[Neutrophils|Neutrophils]]===

[[Image:Neutrophil 2.jpg|thumb|right|150px|Neutrophils - J. Bredl, RVC 2008]]

[[Image:Neutrophil 2.jpg|thumb|right|150px|Neutrophils - J. Bredl, RVC 2008]]

* Neutrophils are the principal, highly active '''phagocytes''' in the blood

* Neutrophils are the principal, highly active '''phagocytes''' in the blood

** Neutrophil activation in an inflammatory lesion results in the release of '''prostaglandins'''

** Neutrophil activation in an inflammatory lesion results in the release of '''prostaglandins'''

*** Responsible for vasoactive changes and for pain

*** Responsible for vasoactive changes and for pain

* The accumulation of dead and dying [[Neutrophils - WikiBlood|neutrophils]] at the site of infection is called '''pus'''

* The accumulation of dead and dying [[Neutrophils|neutrophils]] at the site of infection is called '''pus'''

** Their removal from the site after the removal of infection is an important step in the resolution of the lesion

** Their removal from the site after the removal of infection is an important step in the resolution of the lesion

===[[Eosinophils - WikiBlood|Eosinophils]]===

===[[Eosinophils - WikiBlood|Eosinophils]]===

[[Image:Eosinophil.jpg|thumb|right|150px|Eosinophil - J. Bredl, RVC 2008]]

[[Image:Eosinophil.jpg|thumb|right|150px|Eosinophil - J. Bredl, RVC 2008]]

* Eosinophils are less common than [[Neutrophils - WikiBlood|neutrophils]], and they are not phagocytic

* Eosinophils are less common than [[Neutrophils|neutrophils]], and they are not phagocytic

** Make up <5% of the leukocytes in normal blood

** Make up <5% of the leukocytes in normal blood

* Eosinophil numbers are increased:

* Eosinophil numbers are increased: