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| '''Life Cycle''' | | '''Life Cycle''' |
− | *Large schizonts of ''C. felis'' develop in [[Macrophages - WikiBlood|macrophages]] | + | *Large schizonts of ''C. felis'' develop in [[Macrophages|macrophages]] |
| **In Theileria the exoerythrocytic stage occurs primarily within [[Lymphocytes|lymphocytes]] | | **In Theileria the exoerythrocytic stage occurs primarily within [[Lymphocytes|lymphocytes]] |
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| *Merozoites are then believed to enter erythrocytes to form the intraerythrocytic stage | | *Merozoites are then believed to enter erythrocytes to form the intraerythrocytic stage |
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− | *Merozoites appear in [[Macrophages - WikiBlood|macrophages]] one to three days before they are observed in [[Erythrocytes - WikiBlood|erythrocytes]] | + | *Merozoites appear in [[Macrophages|macrophages]] one to three days before they are observed in [[Erythrocytes - WikiBlood|erythrocytes]] |
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| '''Pathogenicity''' | | '''Pathogenicity''' |
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| *Gross findings include pale or icteric mucous membranes, petechiae and ecchymoses in the [[Lungs - Anatomy & Physiology|lung]], [[Heart - Anatomy & Physiology|heart]], [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and on mucous membranes, splenomegaly, lymphadenomegaly, and hydropericardium | | *Gross findings include pale or icteric mucous membranes, petechiae and ecchymoses in the [[Lungs - Anatomy & Physiology|lung]], [[Heart - Anatomy & Physiology|heart]], [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and on mucous membranes, splenomegaly, lymphadenomegaly, and hydropericardium |
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− | *Microscopically, numerous large schizonts are present within the cytoplasm of endothelial-associated [[Macrophages - WikiBlood|macrophages]] | + | *Microscopically, numerous large schizonts are present within the cytoplasm of endothelial-associated [[Macrophages|macrophages]] |
| **Infected macrophages become markedly enlarged (up to 75μm) and may occlude the lumen of numerous vessels of many tissues, in particular the [[Lungs - Anatomy & Physiology|lungs]] | | **Infected macrophages become markedly enlarged (up to 75μm) and may occlude the lumen of numerous vessels of many tissues, in particular the [[Lungs - Anatomy & Physiology|lungs]] |
| **Minimal inflammatory reaction is present in tissues | | **Minimal inflammatory reaction is present in tissues |