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Text replace - 'Basophils - WikiBlood' to 'Basophils'
===Type I reactions===
===Type I reactions===
*Mediated by pharmacologically active substances from [[Mast Cells - WikiBlood|mast cells]] and [[Basophils - WikiBlood|basophils]]
*Mediated by pharmacologically active substances from [[Mast Cells - WikiBlood|mast cells]] and [[Basophils|basophils]]
**Due to antigen-antibody (usually IgE) binding to receptors on those cells
**Due to antigen-antibody (usually IgE) binding to receptors on those cells
*Substances include histamine, serotonin, leukotriens, prostaglandins
*Substances include histamine, serotonin, leukotriens, prostaglandins
*Microscopically:
*Microscopically:
**Hyperplastic superficial perivascular dermatitis
**Hyperplastic superficial perivascular dermatitis
**Oedema, [[Mast Cells - WikiBlood|mast cells]], [[Basophils - WikiBlood|basophils]], [[Eosinophils - WikiBlood|eosinophils]], [[Lymphocytes|lymphocytes]], histiocytes
**Oedema, [[Mast Cells - WikiBlood|mast cells]], [[Basophils|basophils]], [[Eosinophils - WikiBlood|eosinophils]], [[Lymphocytes|lymphocytes]], histiocytes
**Fibropruritic nodules covered by hyperplastic epidermis
**Fibropruritic nodules covered by hyperplastic epidermis