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Text replace - 'Immunoglobulins - WikiBlood' to 'Immunoglobulins'
{{toplink
{{toplink
|linkpage =Immunoglobulins - WikiBlood
|linkpage =Immunoglobulins
|linktext =IMMUNOGLOBULINS
|linktext =IMMUNOGLOBULINS
|sublink1 =Flash Cards - WikiBlood
|sublink1 =Flash Cards - WikiBlood
|q1=What are immunoglobulins also known as?
|q1=What are immunoglobulins also known as?
|a1=Antibodies
|a1=Antibodies
|l1=Immunoglobulins - WikiBlood#Introduction
|l1=Immunoglobulins#Introduction
|q2=How many domains does the heavy chain have?
|q2=How many domains does the heavy chain have?
|a2=
|a2=
*1 variable domain
*1 variable domain
*3 or 4 constant domains
*3 or 4 constant domains
|l2=Immunoglobulins - WikiBlood#Structure
|l2=Immunoglobulins#Structure
|q3=How many domains does the light chain have?
|q3=How many domains does the light chain have?
|a3=
|a3=
*1 variable domain
*1 variable domain
*1 constant domain
*1 constant domain
|l3=Immunoglobulins - WikiBlood#Structure
|l3=Immunoglobulins#Structure
|q4=What are hypervariable domains?
|q4=What are hypervariable domains?
|a4=
|a4=
*Folded pockets of the variable domain into which antibody can bind
*Folded pockets of the variable domain into which antibody can bind
*Different antibodies have different amino acid sequences within the three variable domains
*Different antibodies have different amino acid sequences within the three variable domains
|l4=Immunoglobulins - WikiBlood#Structure
|l4=Immunoglobulins#Structure
|q5=What does Fab stand for and from which chain is it generated?
|q5=What does Fab stand for and from which chain is it generated?
|a5=
|a5=
*Fragment associated with antigen binding
*Fragment associated with antigen binding
*Light chain
*Light chain
|l5=Immunoglobulins - WikiBlood#Structure
|l5=Immunoglobulins#Structure
|q6=What does Fc stand for and from which chain is it generated?
|q6=What does Fc stand for and from which chain is it generated?
|a6=
|a6=
*Constant fragment
*Constant fragment
*Heavy chain
*Heavy chain
|l6=Immunoglobulins - WikiBlood#Structure
|l6=Immunoglobulins#Structure
|q7=What does the Fc fragment do?
|q7=What does the Fc fragment do?
|a7=Mediates phagocytosis
|a7=Mediates phagocytosis
*Triggers inflammation
*Triggers inflammation
*Targets Ig to certain tissues
*Targets Ig to certain tissues
|l7=Immunoglobulins - WikiBlood#Structure
|l7=Immunoglobulins#Structure
|q8=What are the four major effects of antibodies?
|q8=What are the four major effects of antibodies?
|a8=
|a8=
*Degranulation of mast cells/eosinophils
*Degranulation of mast cells/eosinophils
*Complement Fixation
*Complement Fixation
|l8=Immunoglobulins - WikiBlood#Function
|l8=Immunoglobulins#Function
</FlashCard>
</FlashCard>
===Classes of Immunoglobulin===
===Classes of Immunoglobulin===
|q1=How do the five classes of immunoglobulins vary from each other?
|q1=How do the five classes of immunoglobulins vary from each other?
|a1=They each have a different composition to their heavy chains
|a1=They each have a different composition to their heavy chains
|l1=Immunoglobulins - WikiBlood#Classes
|l1=Immunoglobulins#Classes
|q2=IgA is specially adapted for function at which type of surface?
|q2=IgA is specially adapted for function at which type of surface?
|a2=Mucosal surfaces
|a2=Mucosal surfaces
*IGH genes
*IGH genes
*Heavy chain
*Heavy chain
|l1=Immunoglobulins - WikiBlood#Variation
|l1=Immunoglobulins#Variation
|q2=Complete the sentences about IgG subtypes:
|q2=Complete the sentences about IgG subtypes:
<p>Humans and rodents have ??? IgG subtypes. Dogs have ??? IgG subtypes. Ruminats have ??? IgG subtypes.</p>
<p>Humans and rodents have ??? IgG subtypes. Dogs have ??? IgG subtypes. Ruminats have ??? IgG subtypes.</p>
*three
*three
*three or four
*three or four
|l2=Immunoglobulins - WikiBlood#Variation
|l2=Immunoglobulins#Variation
|q3=What are allotypes?
|q3=What are allotypes?
|a3=
|a3=
*Differences in immunoglobulins between individuals of a particular species
*Differences in immunoglobulins between individuals of a particular species
*Allotypes are inheritable
*Allotypes are inheritable
|l3=Immunoglobulins - WikiBlood#Allo & Idiotypes
|l3=Immunoglobulins#Allo & Idiotypes
|q4=What are idiotypes?
|q4=What are idiotypes?
|a4=Variations in the sequences of amino acids in the variable regions of the light and heavy chains
|a4=Variations in the sequences of amino acids in the variable regions of the light and heavy chains
|l4=Immunoglobulins - WikiBlood#Allo & Idiotypes
|l4=Immunoglobulins#Allo & Idiotypes
|q5=What is immunoglobulin heavy chain switching?
|q5=What is immunoglobulin heavy chain switching?
|a5=
|a5=
*Other classes of immunoglobluins are synthesised
*Other classes of immunoglobluins are synthesised
*The same varibale domains are kept
*The same varibale domains are kept
|l5=Immunoglobulins - WikiBlood#Immunoglobulin Class Switching
|l5=Immunoglobulins#Immunoglobulin Class Switching
|q6=How do different classes of antibody differ from each other?
|q6=How do different classes of antibody differ from each other?
|a6=
|a6=
*Associated carbohydrate
*Associated carbohydrate
*Function
*Function
|l6=Immunoglobulins - WikiBlood#Immunoglobulin Class Switching
|l6=Immunoglobulins#Immunoglobulin Class Switching
</FlashCard>
</FlashCard>