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Created page with '{{review}} <br> <p>''Shortened to IgD''</p> thumb|150px|right|'''IgD''' thumb|right|150px|IgD - B. Catchpole, RVC 2008 <p>IgD is present in…'
{{review}}
<br>
<p>''Shortened to IgD''</p>
[[Image:LH IgD.png|thumb|150px|right|'''IgD''']]
[[Image:IgD.jpg|thumb|right|150px|IgD - B. Catchpole, RVC 2008]]
<p>IgD is present in ruminants, pigs, (dogs) and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted.</p>
==Structure==
<p>IgD is Y-shaped and in rodents it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.</p>
==Function==
<p>
*IgD is only expressed in association with IgM
*It is important in B-cell development. </p>
<br>
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<center><b><sup>[[Immunoglobulins|Immunoglobulins]]: [[Immunoglobulin A|Immunoglobulin A]], [[Immunoglobulin D - WikiBlood|Immunoglobulin D]], [[Immunoglobulin E - WikiBlood|Immunoglobulin E]], [[Immunoglobulin G - WikiBlood|Immunoglobulin G]] & [[Immunoglobulin M - WikiBlood|Immunoglobulin M]]</sup></b></center>
<br>
<p>''Shortened to IgD''</p>
[[Image:LH IgD.png|thumb|150px|right|'''IgD''']]
[[Image:IgD.jpg|thumb|right|150px|IgD - B. Catchpole, RVC 2008]]
<p>IgD is present in ruminants, pigs, (dogs) and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted.</p>
==Structure==
<p>IgD is Y-shaped and in rodents it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.</p>
==Function==
<p>
*IgD is only expressed in association with IgM
*It is important in B-cell development. </p>
<br>
----
<center><b><sup>[[Immunoglobulins|Immunoglobulins]]: [[Immunoglobulin A|Immunoglobulin A]], [[Immunoglobulin D - WikiBlood|Immunoglobulin D]], [[Immunoglobulin E - WikiBlood|Immunoglobulin E]], [[Immunoglobulin G - WikiBlood|Immunoglobulin G]] & [[Immunoglobulin M - WikiBlood|Immunoglobulin M]]</sup></b></center>