Author, Donkey, Bureaucrats, Administrators
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*Common in dogs: especially subvalvular lesions; Boxers usually have valvular stenosis
*Common in dogs: especially subvalvular lesions; Boxers usually have valvular stenosis
-Sudden death within the first 1-3 years of life
-Sudden death within the first 1-3 years of life
==From Pathology==
Obstructs blood flow from the left ventricle to the aorta. Stenosis may be:
*Subvalvular (most common in dog and cat).
*Valvular.
*Supravalvular.
Subvalvular stenosis results in a jet of blood hitting the aortic valve, leading to damage and increased risk of developing endocarditis.
''Incidence:''
*Increased prevalence in Boxers and Golden retrievers.
*Autosomal dominant in Newfoundlands.
''Clinical Signs:''
*Vary from asymptomatic to degrees of exercise intolerance, syncope and even sudden death.
*Harsh systolic murmur at left heart base.
Grade correlates with grade of murmur.
High grade murmurs also have a precordial thrill.
*Murmur may have a diastolic component due to aortic valve damage and insufficiency.
*Weak femoral pulse.
''Diagnosis:''
*Left ventricular enlargement on radiology and ECG.
*Post-stenotic dilatation of the aorta may be visible on radiographs.
*Echogenic fibrous ring may be seen on echocardiography. Again, Doppler is useful to detect flow rates.
''Treatment:''
*'''Balloon valvuloplasty'''; often unsuccessful.
*Mild cases need no management.
*Medical management; Beta-blockers to decrease myocardial oxygen consumption.
*Prognosis guarded, death due to arrythmias in abnormal myocardium.
[[Category:Cardiovascular_System_-_Developmental_Pathology]]