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Created page with '*Clinical signs and epidemiology: **Acute disease in susceptible herds with high morbidity and mortality (up to 50%) **In acute outbreaks, pigs may be dyspnoeic, pyrexic or anore…'
*Clinical signs and epidemiology:
**Acute disease in susceptible herds with high morbidity and mortality (up to 50%)
**In acute outbreaks, pigs may be dyspnoeic, pyrexic or anorexic
**Blood-stained froth surrounding nose and mouth
**Cyanosis
**Pregnant sows abort
**Causes [[Respiratory Bacterial Infections - Pathology#Actinobacillus pleuropneumoniae|pneumonia]] in pigs
**Carrier herds have some immunity, protecting from acute disease, where lesions are often subclinical, and deaths sporadic
**Lung scarring and pleural adhesions in many recovered animals
**Solid immunity develops in recovered animals to all serotypes
**The disease is spread between herds by carrier pigs
*Diagnosis:
**Haemorrhagic consolidation close to the main bronchi and fibrinous pleuritis may be suggestive
**Specimens are cultured on chocolate agar and blood agar in 5-10% carbon dioxide for 2-3 days
**Small colonies surrounded by clear haemolysis
**No growth on MacConkey agar
**Positive CAMP reaction with ''[[Staphylococcus aureus]]''
**Most strains are NAD-dependent (grow on Heated Blood agar)
**Immunofluorescent- or PCR-based techniques
**The bacteria on the [[Tonsils - Anatomy & Physiology#Palatine|palatine tonsil]] may remain undetected by serological tests and swabbing, and can therefore cause an outbreak in naive pigs
*Treatment:
**Antibiotics depending on the strain of bacteria
**Prophylactic antibiotics for in-contact pigs
*Control:
**Killed and polyvalent bacterin vaccines as well as a subunit vaccine are available
**Improve ventilation, avoid chilling and overcrowding
[[Category:Pig]][[Category:To_Do_-_Clinical]]
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