Changes

===Histopathology===

===Histopathology===

Liver cytology or tissue biopsy is required to differentiate inflammatory liver disease from [[Hepatic Lipidosis - WikiClinical|hepatic lipidosis]] and [[Neoplasia - Pathology|neoplasia]].  Bile samples for cytology is needed for a definitive diagnosis.  It is not adequate to perform liver biopsy alone as the disease tend to be confined to the biliary tract and pathology of the liver can be non specific and  mild.  Cytologically, neutrophilic cholangitis usually shows bacteria and [[Neutrophils|neutrophils]].  Culture and sensitivity should be performed for appropriate choice of antibiotics.

Liver cytology or tissue biopsy is required to differentiate inflammatory liver disease from [[Hepatic Lipidosis|hepatic lipidosis]] and [[Neoplasia - Pathology|neoplasia]].  Bile samples for cytology is needed for a definitive diagnosis.  It is not adequate to perform liver biopsy alone as the disease tend to be confined to the biliary tract and pathology of the liver can be non specific and  mild.  Cytologically, neutrophilic cholangitis usually shows bacteria and [[Neutrophils|neutrophils]].  Culture and sensitivity should be performed for appropriate choice of antibiotics.

**Fluid and electrolyte derangements should be corrected.

**Fluid and electrolyte derangements should be corrected.

**Vitamin K1 may be given if bleeding diatheses develop.

**Vitamin K1 may be given if bleeding diatheses develop.

*A high protein diet rather than a protein-restricted diet is more appropriate for feeding anorexic cats to prevent the development of [[Hepatic Lipidosis - WikiClinical|hepatic lipidosis]]

*A high protein diet rather than a protein-restricted diet is more appropriate for feeding anorexic cats to prevent the development of [[Hepatic Lipidosis|hepatic lipidosis]]

*Monitor response to treatment with serial complete haematology and biochemistry.

*Monitor response to treatment with serial complete haematology and biochemistry.