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*To aid [[Ectoparasiticides|acaricide]] penetration, clipping a dog's coat and washing is recommended
*To aid [[Ectoparasiticides|acaricide]] penetration, clipping a dog's coat and washing is recommended
*[[Demodex|''Demodex'']] are normal inhabitants of hair follicles and sebaceous glands
*Have to have increased number of immature mites to classify as infestation
*Host-specific
*Occurs in dogs, cattle, sheep, goats, pigs, horses and cats
*Transmits during nursing from dam to offspring
*''Demodex canis'' in dogs:
**Generalised or localised
**Mainly young dogs affected or adults with other disease ([[Adrenal Glands - Pathology#Adrenal Hyperfunction|hyperadrenocorticism]], [[Thyroid Gland - Pathology#Hypothyroidism|hypothyroidism]])
**Often inherited in pure bred
**Grossly:
***Localised: scaly, erythematous, macular, alopecic areas; usually face or front legs
***Generalised: large, coalescing lesions, patches, erythema, alopecia, scales, crusts
**Microscopically:
***Localised: lymphoplasmacytic perifolliculitis with hyperkeratinisation, sebaceous adenitis, low pigment, intraluminal mites
***Generalised: perifolliculitis and follicular hyperkeratosis, follicular pluggingf, bacterial proliferation, bacterial neutrophilic folliculitis
****May cause folliculat rupture -> furunculosis, cellulitis, lymphadenitis and septicaemia
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