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, 10:46, 30 June 2010
*Local reaction depends on host hypersensitivity and [[Ticks|tick's]] secretions
*Grossly:
**Focal erosions, erythema, crusted ulcers, sometimes alopecia and nodules
*Microscopically:
**Epidermal and dermal necrosis
**Perivascular of diffuse inflammation and necrotic margins
**Eosinophils, macrophages and lymphocytes in exudate
**May form granulomas containing collagenous fibres and lymphoid follicles within dermis
[[Category:To_Do_-_Clinical]]