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− | *Caused by [[Sporothrix schenckii|''Sporothrix schenckii'']]
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− | *Cutaneous, may involve lymhatic vessels or disseminate | + | |
− | *Occurs in horses, cattle, cats and dogs | + | |
− | *Grossly: | + | [[Image:Sporotrichosis horse.jpg|thumb|right|150px|Sporotrichosis in a horse -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]] |
− | **Ulcerated cutaneous nodules | + | [[Image:Sporotrichosis cigar cells.jpg|thumb|right|150px|Sporotrichosis cigar shaped cells -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]] |
− | **Fistulas may form | + | *''Sporothrix schenckii'' |
− | *Microscopically: | + | |
− | **Hard to find ovoid to elongated organisms | + | *Occurs in soil, wood and vegetation |
− | **More numerous in cats | + | **Saprophyte of both decaying and healthy vegetation |
− | *Exudate may be infectious to humans if comes into contact with wounds | + | |
| + | *Worldwide |
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| + | *Exogenous infections through wounds |
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| + | *Sporadic infections |
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| + | *Non-contageous |
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| + | *Causes subcutaneous nodules or granulomas |
| + | **Nodules ulcerate discharging pus |
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| + | *Spread via the [[Lymphatic System - Anatomy & Physiology|lymphatics]] |
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| + | *The [[Bones and Cartilage - Anatomy & Physiology|bones]] and viscera can be involved which terminates in mortality |
| + | **This is rare |
| + | **Reported in dogs and horses |
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| + | *Affects dogs, horses, cats, monkeys, mules, camels, donkeys, cattle, fowl and rodents |
| + | **Most commonly seen in horses as an ascending lymphocutaneous infection of the legs |
| + | **Can be confused with [[Subcutaneous Mycoses#Epizootic Lymphangitis|epizootic lymphangitis]] in horses |
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| + | *Single cell, cigar shaped |
| + | **Usually found within [[Neutrophils|neutrophils]] |
| + | **Yeast cell clusters with peripheral eosinophilic rays can be seen in tissue sections |
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| + | *Stained using PAS, Gram stain (positive), fluorescent antibody and Calcofluor White |
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| + | *Latex agglutination and immunodiffusion serology can be performed |
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| + | *Grows on Blood agar and Sabouraud's Dextrose agar in one to three weeks |
| + | **At 37°C: |
| + | ***Colonies are smooth, cream to tan coloured and soft |
| + | ***No mycelium can be seen |
| + | **At 25°C to 27°C: |
| + | ***Colonies turn from white and soft to tan to brown to black |
| + | ***Leathery, wrinkled and coarse |
| + | ***Mycelium can be seen as branching septate hyphae |
| + | ***Conidiospores can also be seen |
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| + | *Potassium iodide treatment orally |
| + | **[[Antifungal Drugs#Flucytosine|5-fluorocytosine]] and [[Antifungal Drugs#Polyene Antifungals|amphotericin B]] can also be used[[Category:Subcutaneous_Mycoses]] |
| + | [[Category:To_Do_-_Fungi]] |