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Bovine Respiratory Syncytial Virus (view source)
Revision as of 12:06, 30 June 2010
, 12:06, 30 June 2010no edit summary
====Secondary Concerns====
====Secondary Concerns====
*<small>'''Reference''': Bryson, 1999, Update on calf pneumonia, CPD Veterinary Medicine, 1,3, 90-95</small>
*<small>'''Reference''': Bryson, 1999, Update on calf pneumonia, CPD Veterinary Medicine, 1,3, 90-95</small>
*Causative agent [[Paramyxoviridae|Respiratory syncytial virus (RSV)]], synonym: bovine RSV (BRSV)
*Outbreaks of RSV associated disease usually occur associated with winter housing
*Gross pathology in severe cases
**Cranioventral [[Lungs Ventilation - Pathology#Atelectasis (Collapse)|atelectasis]] and consolidation
**[[Lungs Ventilation - Pathology#Emphysema|Interstitial emphysema]]
***More prominent in the caudal lung lobes
***Results from bronchoconstriction which results in airway obstruction - this constriction is thought to arise from [[Mast Cells|mast cell]] degranulation and histamine release
*Histologically
**[[Bronchi and Bronchioles Inflammatory - Pathology#Acute bronchitis/bronchiolitis|Acute bronchiolitis]], characteristic of the bronchiolar response is the formation of syncytial giant cells (formed by proliferating bronchiolar epithelial cells which may contain [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|intracytoplasmic inclusion bodies]]), alveolar epithelium sometimes affected
**Obstruction of bronchioles by exudate - these may later become obliterated by the fibrous tissue of organisation
*May contribute to [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]
[[Category:Pneumovirinae]][[Category:Cattle]]
[[Category:Pneumovirinae]][[Category:Cattle]]
[[Category:To_Do_-_Viruses]]
[[Category:To_Do_-_Viruses]]