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*Seropositive and progeny must be removed from flock
*Seropositive and progeny must be removed from flock
*Farm can be re-accredited after 2 years of clear tests
*Farm can be re-accredited after 2 years of clear tests
*Caused by a [[Retroviridae|retrovirus]]
*The respiratory from of the disease caused by maedi-visna virus (Maedi) is also called '''lymphoid interstitial pneumonia'''
*Transmitted by close contact and via milk
*The pulmonary lesions develop very slowly hence this disease is uncommon in sheep < 2 years old
*Increased respiratory rate upon exertion, loss of weight
*Remains in [[Monocytes]] and macrophages
*Gross findings
**Severe [[Lungs Inflammatory - Pathology#Interstitial pneumonia|interstitial pneumonia]]
**Lungs fail to collapse properly on opening the chest and can weigh more than twice the normal weight
**Impressions of the ribs remain on the visceral pleura
**Lungs are a mottled grey/ tan colour - the lesions can vary from irregular grey speckling to homogeneous grey consolidation
**Rubbery in consistence
**Diaphragmatic lobes most affected
**Associated bronchial and mediastinal lymph nodes are often enlarged
*Histologically
**Major features are extensive lymphoid proliferation around perivascular, peribronchial and peribronchiolar sheaths associated with pulmonary lymphatics
**Many of these areas contain germinal centres and smooth muscle hyperplasia (in walls of terminal bronchioles and alveoli)
[[Category:Lentiviruses]][[Category:Sheep]]
[[Category:Lentiviruses]][[Category:Sheep]]
[[Category:To_Do_-_Viruses]]
[[Category:To_Do_-_Viruses]]