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New page: right|thumb|125px|<small><center>'''Sarcoma embolus (dog)'''. Courtesy of T. Scase</center></small> ===Description=== *As the name implies, a thromboembolis...
[[Image:sarcoma embolus.jpg|right|thumb|125px|<small><center>'''Sarcoma embolus (dog)'''. Courtesy of T. Scase</center></small>]]
===Description===
*As the name implies, a thromboembolism is a clot (thrombus) or foreign body that blocks vessels a distance away from its original site of origin.
*The most significant sites of thromboembolic formation are the following: lungs, CNS, terminal aorta, kidneys.
'''Requirements for thromboembolism formation:
'''
1. Disruption of endothelial integrity
2. Disruption of flow
3. Disruption of blood haemostasis
4. Disruption of fibrinolysis
'''The incidence of thromboembolism greatly increases with certain diseases including:
'''
-Heart Disease
-Neoplasia
-Blood Disorders
-Parasitic Diseases
-Hyperadrenocorticism
====Diagnosis====
=====History & Clinical Signs=====
'''5 P's:'''
-Pain
-Paresis
-Pallor
-Pulselessness
-Polar (cold extremities)
'''Long Term Effects:'''
-Necrosis
'''Specific Problems:'''
*Signs are dependant on site of thromboembolism
-Neurological problems (acute)
-Renal Failure (acute)
-Dyspnoea (acute)
====Laboratory Findings====
*Heavily dependent on thromboembolic site
-Hyperkalemia
-Acidosis
-Increased Lactate
-Azotemia
-Elevated serum creatine phospohokinase
====Radiography, Echocardiography, Angiography====
-Clots may be seen by the above methods
===Treatment===
-Treat underlying conditions
-Pain Relief (e.g. morphine)
-Support with IV fluids
-Anticoagulants:
1. Heparin
2. Aspirin
===Prognosis===
-Grave[[Category:Arterial_Pathology]][[Category:To_Do_-_Cardiovascular]]
===Description===
*As the name implies, a thromboembolism is a clot (thrombus) or foreign body that blocks vessels a distance away from its original site of origin.
*The most significant sites of thromboembolic formation are the following: lungs, CNS, terminal aorta, kidneys.
'''Requirements for thromboembolism formation:
'''
1. Disruption of endothelial integrity
2. Disruption of flow
3. Disruption of blood haemostasis
4. Disruption of fibrinolysis
'''The incidence of thromboembolism greatly increases with certain diseases including:
'''
-Heart Disease
-Neoplasia
-Blood Disorders
-Parasitic Diseases
-Hyperadrenocorticism
====Diagnosis====
=====History & Clinical Signs=====
'''5 P's:'''
-Pain
-Paresis
-Pallor
-Pulselessness
-Polar (cold extremities)
'''Long Term Effects:'''
-Necrosis
'''Specific Problems:'''
*Signs are dependant on site of thromboembolism
-Neurological problems (acute)
-Renal Failure (acute)
-Dyspnoea (acute)
====Laboratory Findings====
*Heavily dependent on thromboembolic site
-Hyperkalemia
-Acidosis
-Increased Lactate
-Azotemia
-Elevated serum creatine phospohokinase
====Radiography, Echocardiography, Angiography====
-Clots may be seen by the above methods
===Treatment===
-Treat underlying conditions
-Pain Relief (e.g. morphine)
-Support with IV fluids
-Anticoagulants:
1. Heparin
2. Aspirin
===Prognosis===
-Grave[[Category:Arterial_Pathology]][[Category:To_Do_-_Cardiovascular]]