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| | *Anticoagulants should be used with caution as the patient will be prone to haemorrhage. | | *Anticoagulants should be used with caution as the patient will be prone to haemorrhage. |
| | *Transfusion with fresh frozen plasma to provide clotting factors and platelets. | | *Transfusion with fresh frozen plasma to provide clotting factors and platelets. |
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| | + | * Disseminated intravacular coagulation is a widespread intravascular coagulation of the microcirculation. |
| | + | * The capillaries are principally affected. |
| | + | * There are various causes. |
| | + | ** Mismatched blood transfusion |
| | + | ** Acute haemolytic crises |
| | + | ** Extensive burns and trauma |
| | + | ** Infectious and post-infectious immunologic reactions. |
| | + | * There is widespread occlusion of the microcirculation with small white thrombi. |
| | + | ** May cause [[Shock - Pathology|shock]], acute respiratory distress, heart failure or renal failure. |
| | + | * Haemorrhagic diathesis may develop. |
| | + | ** Is a result of rapid consumption and depletion of fibrinogen, platelets and clotting factors |
| | + | * The fibrinolytic system is also highly stimulated to prevent what little clotting activity that remains. |
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| | [[Category:Cardiovascular_System_-_Vascular_Pathology]][[Category:Cardiovascular_System_-_Inflammatory_Pathology]][[Category:Arterial_Pathology]] | | [[Category:Cardiovascular_System_-_Vascular_Pathology]][[Category:Cardiovascular_System_-_Inflammatory_Pathology]][[Category:Arterial_Pathology]] |
| | [[Category:To_Do_-_Cardiovascular]] | | [[Category:To_Do_-_Cardiovascular]] |