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==Description==
==Description==
*adenovirus - [[Canine Adenovirus 1]]
*acute and generalised infection
*highly infectious
*spread via the urine of infected animals over a long period of time
==Signalment==
==Signalment==
*young dogs
==Diagnosis==
==Diagnosis==
==Clinical Signs==
===Clinical Signs===
*recovering animals may show an immune-mediated uveitis with corneal opacity
==Laboratory Tests==
===Laboratory Tests===
==Radiography==
===Radiography===
==Biopsy==
===Biopsy===
==Endoscopy==
===Endoscopy===
==Pathology==
===Pathology===
====Gross====
*the virus has a tropism for endothelium and hepatocytes
*the virus has a tropism for endothelium and hepatocytes
**widespread haemorrhages, especially on serosal surface
**widespread haemorrhages, especially on serosal surface
*[[Gall Bladder - Anatomy & Physiology|gall bladder]]
*[[Gall Bladder - Anatomy & Physiology|gall bladder]]
**wall usually shows oedema (up to 2cm diameter)
**wall usually shows oedema (up to 2cm diameter)
*[[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and [[Tonsils - Anatomy & Physiology|tonsils]] are enlarged and reddened, sometimes haemorrhagic
====Microscopically====
*basophilic intranuclear inclusion bodies
*basophilic intranuclear inclusion bodies
**in hepatocytes and macrophages
**in hepatocytes and macrophages
==Treatment==
==Prognosis==
==References==
[[Category:Hepatitis, Viral]][[Category:Dog]][[Category:To_Do_-_Clinical]]
[[Category:Hepatitis, Viral]][[Category:Dog]][[Category:To_Do_-_Clinical]]
[[Category:To_Do_-_Lizzie]]
[[Category:To_Do_-_Lizzie]]