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==Description==
 
==Description==
 +
*adenovirus - [[Canine Adenovirus 1]]
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*acute and generalised infection
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*highly infectious
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*spread via the urine of infected animals over a long period of time
    
==Signalment==
 
==Signalment==
 
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*young dogs
 
==Diagnosis==
 
==Diagnosis==
   −
==Clinical Signs==
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===Clinical Signs===
 
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*recovering animals may show an immune-mediated uveitis with corneal opacity
==Laboratory Tests==
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===Laboratory Tests===
   −
==Radiography==
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===Radiography===
   −
==Biopsy==
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===Biopsy===
   −
==Endoscopy==
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===Endoscopy===
   −
==Pathology==
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===Pathology===
 
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====Gross====
==Treatment==
  −
 
  −
==Prognosis==
  −
 
  −
==References==
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  −
 
  −
*adenovirus - [[Canine Adenovirus 1]]
  −
*also known as Rubarth's Disease, Canine adenovirus infection
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*acute and generalised infection
  −
*young dogs
  −
*highly infectious
  −
*spread via the urine of infected animals over a long period of time
  −
=====Clinical=====
  −
*[[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and [[Tonsils - Anatomy & Physiology|tonsils]] are enlarged and reddened, sometimes haemorrhagic
  −
*recovering animals may show an immune-mediated uveitis with corneal opacity
  −
=====Gross=====
   
*the virus has a tropism for endothelium and hepatocytes
 
*the virus has a tropism for endothelium and hepatocytes
 
**widespread haemorrhages, especially on serosal surface
 
**widespread haemorrhages, especially on serosal surface
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*[[Gall Bladder - Anatomy & Physiology|gall bladder]]
 
*[[Gall Bladder - Anatomy & Physiology|gall bladder]]
 
**wall usually shows oedema (up to 2cm diameter)
 
**wall usually shows oedema (up to 2cm diameter)
 
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*[[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and [[Tonsils - Anatomy & Physiology|tonsils]] are enlarged and reddened, sometimes haemorrhagic
=====Microscopically=====
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====Microscopically====
 
*basophilic intranuclear inclusion bodies
 
*basophilic intranuclear inclusion bodies
 
**in hepatocytes and macrophages
 
**in hepatocytes and macrophages
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==Treatment==
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 +
==Prognosis==
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==References==
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 +
    
[[Category:Hepatitis, Viral]][[Category:Dog]][[Category:To_Do_-_Clinical]]
 
[[Category:Hepatitis, Viral]][[Category:Dog]][[Category:To_Do_-_Clinical]]
 
[[Category:To_Do_-_Lizzie]]
 
[[Category:To_Do_-_Lizzie]]
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