Changes

=====Gross Examination=====

=====Gross Examination=====

In the early stage of the disease haemorrhagic tracts will be visible through the liver due to the migratory activity of the larvae. In later stages of the disease diffuse white spots on the capsular surface of the liver will be visible due to the fibrosis of these tracts.

In the early stage of the disease haemorrhagic tracts will be visible through the [[Liver - Anatomy & Physiology|liver]] due to the migratory activity of the larvae. In later stages of the disease diffuse white spots on the capsular surface of the liver will be visible due to the fibrosis of these tracts.

=====Microscopic Examination=====

=====Microscopic Examination=====

*initial haemorrhage and necrosis of parenchyma along the tracts

The early disease will show haemorrhage and necrosis of parenchyma along the tracts created by the migrating larvae. There will be fibrosis at these sites in the later disease as well as evidence of inflammatory response. The inflammatory response consists of infiltration of many [[Eosinophils|eosinophils]], as well as [[Lymphocytes|lymphocytes]] and [[Macrophages|macrophages]].

*later repair by fibrous tissue at foci

 

*inflammatory cell response contains many [[Eosinophils|eosinophils]], as well as [[Lymphocytes|lymphocytes]] and [[Macrophages|macrophages]]