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Lesions that may be observed on histopathological analysis of biopsy samples include:
 
Lesions that may be observed on histopathological analysis of biopsy samples include:
** Inflammatory bowel disease (of various types)
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** Signs of inflammatory bowel disease
 
** Dilated lymphatics
 
** Dilated lymphatics
 
** Lipogranulomatous lymphangitis, especially in Soft-coated Wheaten terriers
 
** Lipogranulomatous lymphangitis, especially in Soft-coated Wheaten terriers
* Intestinal crypts become dilated with mucus, sloughed epithelial cells with or without inflammatory cells.
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*** Intestinal crypts dilated with mucus, sloughed epithelial cells with or without inflammatory cells.
* PLE is also associated with protein losing nephropathy (PLN).
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* PLE may also be associated with protein losing nephropathy (PLN).
 
** PLN may be a chronic sequelae to the PLE.
 
** PLN may be a chronic sequelae to the PLE.
 
** Follows immune complex deposition in the glomerulus, causing glomerulonephritis or glomerulosclerosis.
 
** Follows immune complex deposition in the glomerulus, causing glomerulonephritis or glomerulosclerosis.
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