− | Diagnosis is often based on a history of a penetrating wound, often to the foot, and clinical signs. Affected animals may have no history of vaccination against tetanus. In cases in which an obvious wound is visible, demonstration of '''C. tetani''' in gram-stained smears and by anaerobic culture may be attempted. Severe cases may be easily diagnosed but mild cases may need differentiating from exertional rhabdomyolysis, laminitis, hypocalcaemia and heat stroke. | + | Diagnosis is often based on a history of a penetrating wound, often to the foot, and clinical signs. Affected animals may have no history of vaccination against tetanus. In cases in which an obvious wound is visible, demonstration of ''C. tetani'' in gram-stained smears and by anaerobic culture may be attempted. Severe cases may be easily diagnosed but mild cases may need differentiating from exertional rhabdomyolysis, laminitis, hypocalcaemia and heat stroke. |