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==Description==

==Description==

Tetanus is a highly-fatal infectious disease caused by the neurotoxin of the gram-positive bacterium ''Clostridium tetani'', resulting in spastic paralysis of affected animals. The bacteria causes infection via contamination of wounds and deposition of bacterial spores in tissue. Deep puncture wounds, cuts and surgical sites may all provide sites of entry for infective spores due to the requirement for anaerobic conditions to allow bacterial germination. ''C. tetani'' produces tetanospasmin, a neurotoxin that is transferred to distant sites via the vascular system. This causes inhibition of the release of GABA and glycine from interneurons in the spinal cord and brain, resulting in tetanic spasm of striated muscle. The incubation period varies from one to four weeks depending on the suitability of the wound environment for bacterial multiplication.

Tetanus is a highly-fatal infectious disease caused by the neurotoxin of the gram-positive bacterium ''[[Clostridium tetani]]'', resulting in spastic paralysis of affected animals. The bacteria causes infection via contamination of wounds and deposition of bacterial spores in tissue. Deep puncture wounds, cuts and surgical sites may all provide sites of entry for infective spores due to the requirement for anaerobic conditions to allow bacterial germination. ''C. tetani'' produces tetanospasmin, a neurotoxin that is transferred to distant sites via the vascular system. This causes inhibition of the release of GABA and glycine from interneurons in the spinal cord and brain, resulting in tetanic spasm of striated muscle. The incubation period varies from one to four weeks depending on the suitability of the wound environment for bacterial multiplication.

==Signalment==

==Signalment==

[[Category:To_Do_-_SophieIgnarski]]

[[Category:To_Do_-_SophieIgnarski]]

[[Category:To_Do_-_Review]]

[[Category:To_Do_-_Review]]