Transfer is '''vector'''-mediated, primarily via '''[[Culicidae|mosquito salivary transfer]]'''. Western EEV and Venezuelan EEV may also be transmitted horse to horse through nasal secretions. This mode of transmission is less likely, despite the fact that high concentrations of Venezuelan EEV are found in ocular and nasal discharges from infected horses. The viraemic phase ends when nervous signs develop and is important for disease amplification. Amplification from horses is likely only with Venezuelan EEV, in association with a relatively high viraemia. Similarly, zoonotic spread is unlikely for Eastern and Western EEV, but has been noted with Venezuelan EEV.
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Transfer is '''vector'''-mediated, primarily via '''[[Culicidae|mosquito salivary transfer]]'''. WEE and VEE may also be transmitted horse to horse through nasal secretions. This mode of transmission is less likely, despite the fact that high concentrations of VEE virus are found in ocular and nasal discharges from infected horses. The viraemic phase ends when nervous signs develop and is important for disease amplification. Amplification from horses is likely only with VEE virus, in association with a relatively high viraemia. Similarly, zoonotic spread is unlikely for Eastern and Western equine encephalitis, but has been noted with VEE.