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Campylobacter live on the mucosa of the intestinal and genital tract and can be commensals or pathogens. The enteric species cause disease in humans and other species cause infertility and abortion in cattle and sheep. [[Campylobacteriosis]] is caused by Campylobacter organisms.
 
Campylobacter live on the mucosa of the intestinal and genital tract and can be commensals or pathogens. The enteric species cause disease in humans and other species cause infertility and abortion in cattle and sheep. [[Campylobacteriosis]] is caused by Campylobacter organisms.
 
''C. jejuni'' and ''C. lari'' is excreted in the faeces of birds and pigs and can contaminate water and food supplies.
 
''C. jejuni'' and ''C. lari'' is excreted in the faeces of birds and pigs and can contaminate water and food supplies.
[[Campylobacter fetus subspecies fetus|''C.fetus'']] is restricted to the bovine prepucial mucosa.
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[[Campylobacter fetus subspecies fetus|''C.fetus'']] is restricted to the bovine prepucial mucosa.
    
==Characteristics==
 
==Characteristics==
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==Pathogenesis and pathogenicity==
 
==Pathogenesis and pathogenicity==
''C. fetus'' subspecies [[Campylobacter fetus subspecies fetus|''fetus'']] and subspecies ''venerealis'' possess a microcapsule (S layer) which resists phagocytosis and serum-mediated destruction and enhances survival in the genital tract.
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''C. fetus'' subspecies [[Campylobacter fetus subspecies fetus|''fetus'']] and subspecies [[Campylobacter fetus subspecies venerealis|''venerealis'']] possess a microcapsule (S layer) which resists phagocytosis and serum-mediated destruction and enhances survival in the genital tract.
Antigens of the S layer undergo antigenic shifts in ''C. fetus'' subspecies ''venerealis'', allowing persistence in the host.
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Antigens of the S layer undergo antigenic shifts in ''C. fetus'' subspecies [[Campylobacter fetus subspecies venerealis|''venerealis'']], allowing persistence in the host.
 
''C. jejuni'' attaches and invades host enterocytes and produces enterotoxin-like substances.
 
''C. jejuni'' attaches and invades host enterocytes and produces enterotoxin-like substances.
 
The Flagellae of ''C. jejuni'' required for colonisation.
 
The Flagellae of ''C. jejuni'' required for colonisation.
 
[[Category:To_Do_-_AimeeHicks]]
 
[[Category:To_Do_-_AimeeHicks]]
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