Hypercalcaemia is present in 50%-90% of dogs with anal sac adenocarcinoma. This is thought to occur due to the expression of a gene for parathyroid hormone-related peptide by the tumour. Parathyroid hormone-related peptide has actions similar to parathyroid hormone, it acts to increase calcium levels in the blood. In severe cases of hypercalcaemia organ function can become compromised changing specific parameters on the biochemistry panel. | Hypercalcaemia is present in 50%-90% of dogs with anal sac adenocarcinoma. This is thought to occur due to the expression of a gene for parathyroid hormone-related peptide by the tumour. Parathyroid hormone-related peptide has actions similar to parathyroid hormone, it acts to increase calcium levels in the blood. In severe cases of hypercalcaemia organ function can become compromised changing specific parameters on the biochemistry panel. |