Changes

==Description==

==Description==

==Prevalence==

==Prevalence==

Racehorses 80-100%

Racehorses 80-100% (Hammond et al 1986, Vatistas et al 1994 and 1997, Murray et al 1996)

Show horses 60%

Show horses 60% (McClure et al 1999)

Ponies 78%

Ponies 78% (MacAllister et al 1982)

Endurance 67%

Endurance 67% (Pieto et al 2004)

==Signalment==

==Signalment==

Foals and young horses in training

Foals and young horses in training

*Low-grade colic

*Low-grade colic

*Excessive recumbency

*Excessive recumbency

*Bruxism (in foals only)

*Bruxism (in foals only and almost pathognomonic)

==Diagnosis==

==Diagnosis==

==Pathology==

==Pathology==

==Treatment==

==Treatment==

Proton pump inhibitors: only omeprazole (Gastroguard) is licensed for horses.  Given PO once daily (4mg/kg) for 3-4 wks, most effective drug at controlling HCl secretion (decreases basal and stimulated release)

Proton pump inhibitors: only omeprazole (Gastroguard) is licensed for horses.  Given PO once daily (4mg/kg) for 3-4 wks, most effective drug at controlling HCl secretion (decreases basal and stimulated release).  Expensive and not absorbed in foas with diarrhoea

Histamine H2 receptor antagonists:  

Histamine H2 receptor antagonists:  

*ranitidine 7mg/kg TID for 3-4wks

*ranitidine 7mg/kg TID for 3-4wks

*cimetidine 25mg/kg QID for 3-4wks

*cimetidine 25mg/kg QID for 3-4wks (cheaper but less effective so must be given more frequently)

Gastric protectants: sucralfate 10-20mg/kg TID for 2-4wks

Gastric protectants: sucralfate 10-20mg/kg TID for 2-4wks

Antacids: magnesium and aluminium hydroxides (NOT recommended as have massive rebound effect)

Antacids: magnesium and aluminium hydroxides (NOT recommended as have massive rebound effect)

==Prognosis==

==Prognosis==

==Prevention==

==Prevention==

Gastroguard at lower dose (1mg/kg) daily for 3-4wks

Gastroguard at lower dose (1-2mg/kg) daily for 3-4wks (100, 107-109 in Sanchez)

==References==

==References==

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