− | Colitis X (so-called due to its unknown aetiology) is a peracute and highly fatal disease of horses. Is characterised by severe oedematous colitis, sudden watery diarrhoea and death within 24 hours. A number of possible underlying causes have been described, including drug or parasite hypersensitivity, salmonellosis and high-protein, low-cellulose diets. Clostridium perfringens Type A has been hypothesised to be a cause of Colitis x, and recently a link has been demonstrated with the current human epidemic strain of ''Clostridum difficile'' (ribotype 027/toxinotype III) clostridial enterocolitis. Stress (such as surgery or transport) has also been reported as a predisposing factor. | + | Colitis X (so-called due to its unknown aetiology) is a peracute and highly fatal disease of horses. Is characterised by severe colitis, sudden watery diarrhoea and death within 24 hours. A number of possible underlying causes have been described, including drug or parasite hypersensitivity, stress and transport. ''Clostridium perfringens'' Type A has been hypothesised to be a cause of Colitis x, and high-protein, low-cellulose diets or antimicrobial treatment may predispose to Clostridial mulitplication. Recently a link has been demonstrated with the current human epidemic strain of ''Clostridum difficile'' (ribotype 027/toxinotype III) clostridial enterocolitis. |