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Created page with '{{unfinished}} {| cellpadding="10" cellspacing="0" border="1" | Also known as: |'''Blood Urea Nitrogen - BUN''' |- | See also: |'''Urea in lizards''' |} …'
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{| cellpadding="10" cellspacing="0" border="1"
| Also known as:
|'''Blood Urea Nitrogen - BUN'''
|-
| See also:
|'''[[Blood urea nitrgoen|Urea in lizards]]'''
|}

==Description==
Urea is a form of nitrogenous waste formed from [[Ammonia|ammonia]] via the urea cycle in the liver. It freely crosses lipid membranes and is filtered into the glomerular filtrate in the renal glomerulus. A proportion of this filtered urea is reabsorbed passively before final excretion and it forms a vital of the concentration gradient needed to prevent passive diuresis.

==Clinical Significance==
An increase in serum concentrations of urea and creatinine is known as '''[[Azotaemia|azotaemia]]''' and it is found almost exclusively in animals with kidney disease.

Blood urea coentration may be elevated independently of creatinine for the following reasons:
*Gastro-intestinal haemorrhage, as with [[Gastric Ulcer - Dog|gastro-duodenal ulceration]].
*Diet with high purine content, such as liver.

Reduced urea concentration:

[[Category:Blood_Sample]][[Category:Dog]][[Category:Cat]][[Category:Cattle]][[Category:Sheep]][[Category:Horse]][[Category:Pig]][[Category:Donkey]][[Category:To_Do_-_James]]
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