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Endocrine effects on the skin - Pathology (view source)

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*Castration may temporarily remove symptoms

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===='''Superficial ~~necrolytic dermatopathy~~'''====

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===='''[[Superficial Necrolytic Dermatopathy]]'''====

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*Also known as ''diabetic dermatopathy, hepatocutaneous syndrome''

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*In older dogs with diabetes mellitus, hepatic dysfunction or pancreatic lesions

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*Grossly: scaling and crusting, erythema, facial, genital and distal extremities alopecia, crusting, fissures and ulceration of foot pads

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*Microscopically: trilaminar thickening of epidermis (outermost layer is keratotic, intermediate oedematous and vacuolated, inner is hyperplastic)

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