Changes

==='''Wet form'''===

==='''Wet form'''===

Widespread miliary, white, pinhead granulomas and fibrin deposition, particularly in the serosa of  the [[Small Intestine - Anatomy & Physiology|small intestine]] and [[Large Intestine - Anatomy & Physiology |large intestine]]

Widespread miliary, white, pinhead granulomas and fibrin deposition, particularly in the serosa of  the [[Small Intestine - Anatomy & Physiology|small]] and [[Large Intestine - Anatomy & Physiology |large intestine]]

High-protein exudates can be found in [[Peritoneal cavity - Anatomy & Physiology|peritoneal cavity]].  

High-protein exudates can be found in [[Peritoneal cavity - Anatomy & Physiology|peritoneal cavity]].  

====Histological====

====Histological====

Multifocal pyogranulomas on serosa and throughout gut wall. Infiltration by mononuclear cells, lymphocytes, plasma cells, macrophages and a few[[Neutrophils|neutrophils]]. Necrosis and vasculitis will also be seen.

Multifocal pyogranulomas on serosa and throughout gut wall. Infiltration by mononuclear cells, [[Lymphocytes|lymphocytes]], plasma cells, [[Macrophages|  macrophages]] and a few[[Neutrophils|neutrophils]]. [[Necrosis - Pathology|Necrosis]] and vasculitis will also be seen.

Almost invariably fatal.

Almost invariably fatal.

Immunomodulators including interferon have been used to control the virus and Dr. Diane Addie at Glasgow vet school has found that cats do respond to this form of treatment.   

Immunomodulators including interferon have been used to control the virus and Dr. Diane Addie at Glasgow vet school has found that cats do respond to this form of treatment.   

Immunosuppressive drugs such as prednisolone or cyclophosphamide may slow disease progression.  

Immunosuppressive drugs such as [[Steroids| prednisolone]] or cyclophosphamide may slow disease progression.  

Cats should recieve widespread antibiotics and suppotive therapy.   

Cats should recieve widespread [[Antibiotics|antibiotics]] and suppotive therapy.   

==Control==

==Control==

Conventional vaccination is counterproductive as antibody worsens infection however a non-systemic vaccine (Primucell) is available outside the UK. Replication confined to nasal mucosa, providing local immunity and cell-mediated immunity and it cannot protect cats already infected with FECoV.  

Conventional [[Vaccines - WikiBlood| vaccination]] is counterproductive as antibody worsens infection however a non-systemic vaccine (Primucell) is available outside the UK. Replication confined to nasal mucosa, providing local immunity and cell-mediated immunity and it cannot protect cats already infected with FECoV.  

Antibody tests are available to certify FECoV-free cat houses.

Antibody tests are available to certify FECoV-free cat houses.