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A highly contagious acute respiratory disease spread by close contact causing laryngitis, tracheitis, bronchitis and in some cases a rhinitis.
 
A highly contagious acute respiratory disease spread by close contact causing laryngitis, tracheitis, bronchitis and in some cases a rhinitis.
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Multiple agents are implicated in the disease including [[Canine Adenovirus 1|Canine Adenovirus 1]],[[Canine Adenovirus 2|Canine Adenovirus 2]],[[Canine Herpesvirus 1|Canine Herpes virus]], [[Canine Parainfluenza - 2|Canine Parainfluenza - 2]], [[Canine Distemper Virus|Canine Distemper Virus]], [[Category:Mycoplasmas|Mycoplasma species]] and [[Bordetella bronchiseptica|''Bordetella bronchoseptica'']]. Most cases involve a primary viral infection and sometimes with secondary bacterial involvement. ''B.bronchoseptica'' adheres to ciliated epithelial cells in the trachea where it proliferates and releases toxins causing epithelial necrosis and prevents[[Diseases of the nasal cavity and sinuses#Mucociliary escalator| ciliary clearance]].  Mortality rates are very low and it is a common disease in dogs that are housed in groups.
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Multiple agents are implicated in the disease including [[Canine Adenovirus 1|Canine Adenovirus 1]],[[Canine Adenovirus 2|Canine Adenovirus 2]],[[Canine Herpesvirus 1|Canine Herpes virus]], [[Canine Parainfluenza - 2|Canine Parainfluenza - 2]], [[Canine Distemper Virus|Canine Distemper Virus]], [[:Category:Mycoplasmas|Mycoplasma species]] and [[Bordetella bronchiseptica|''Bordetella bronchoseptica'']]. Most cases involve a primary viral infection and sometimes with secondary bacterial involvement. ''B.bronchoseptica'' adheres to ciliated epithelial cells in the trachea where it proliferates and releases toxins causing epithelial necrosis and prevents[[Diseases of the nasal cavity and sinuses#Mucociliary escalator| ciliary clearance]].  Mortality rates are very low and it is a common disease in dogs that are housed in groups.
    
==Signalment==
 
==Signalment==
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The clinical signs typically persist for 2-3 days to 2-3 weeks.
 
The clinical signs typically persist for 2-3 days to 2-3 weeks.
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Systemic signs are likely to indicate the development of [[Lungs Inflammatory - Pathology#Bronchopneumonia|bronchopneumonia]], signs include pyrexia, inappetance and depression. Systemic disease is more likely to occur in young or immunocompromised animals. This condition is usually a result of secondary infection with [[Category:Pasteurella and Mannheimia species| pasturella species]] pasturella and [[Category:Streptococcus species| streptococci bacteria]] streptococci species. If widespread systemic signs are present infection wth canine distemper virus should be suspected.
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Systemic signs are likely to indicate the development of [[Lungs Inflammatory - Pathology#Bronchopneumonia|bronchopneumonia]], signs include pyrexia, inappetance and depression. Systemic disease is more likely to occur in young or immunocompromised animals. This condition is usually a result of secondary infection with [[:Category:Pasteurella and Mannheimia species| pasturella species]] pasturella and [[:Category:Streptococcus species| streptococci bacteria]] streptococci species. If widespread systemic signs are present infection wth canine distemper virus should be suspected.
    
Diagnosis is most often made on history and physical exam ruling out other causes of the cough.
 
Diagnosis is most often made on history and physical exam ruling out other causes of the cough.
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Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial  
 
Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial  
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