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Gastric Neoplasia - Dog and Cat (view source)
Revision as of 17:07, 27 July 2010
, 17:07, 27 July 2010no edit summary
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==Introduction==
==Description==
Aetiology largely idiopathic though long term ingestion of dietary carcinogens may have some responsibility. Long term administration of nitrosamines may also cause carcinomas in dogs. In humans, ''Helicobacter pylori'' can induce gastric carcinomas and lymphomas. Its role in gastric tumours in dogs and cats has not yet been fully established though it is known to cause gastritis and ulceration. Belgian Shepherd dogs may have a genetic predisposition to gastric carcinomas. Cats with gastric lymphomas are not usually FeLV positive.
Adenocarcinomas: frequently metastasise to the regional lymph nodes (gastroduodenal and splenic lymph nodes), also the liver and sometimes the lungs. They are also locally aggressive and can cause stomach wall perforation resulting in peritonitis. Other complications include:
* Pyloric outflow obstruction
* Ischaemic necrosis - where tumour plugs develop in the surrounding vasculature
Leiomyosarcomas: rarely metastasise.
Lymphoma: may be limited to the stomach, may affect lymph nodes and other abdominal organs or may be multicentric.
Plasmacytoma: metastasis is frequently evident in local lymph nodes.
Malignant tumours include:
* [[Adenocarcinoma|Adenocarcinoma]] - 70-80% of all canine gastric neoplasms
* [[Adenocarcinoma|Adenocarcinoma]] - 70-80% of all canine gastric neoplasms
* [[Squamous Cell Carcinoma|Squamous Cell Carcinoma]]
* [[Squamous Cell Carcinoma|Squamous Cell Carcinoma]]
==Signalment==
==Signalment==
Male dogs are more commonly affected than female: e.g male:female ratio in those with carcinoma 2.5:1
The mean age of dogs with carinomas is 8 years and cats with carcinomas are usually over 10 years. For benign tumours the mean age of affected dogs is 15 years.
==Diagnosis==
==Diagnosis==