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Johne's Disease (view source)

Revision as of 17:24, 27 July 2010

283 bytes removed ,  17:24, 27 July 2010
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In advances cases the infected animal gradually fades away and dies over the course of months.
 
In advances cases the infected animal gradually fades away and dies over the course of months.
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===Pathogenesis===
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==Pathogenesis==
    
Organisms penetrate the M-cells of the [[Peyer's Patches - Anatomy & Physiology|Peyer's patches]].  
 
Organisms penetrate the M-cells of the [[Peyer's Patches - Anatomy & Physiology|Peyer's patches]].  
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===Pathology===
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==Pathology==
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====Gross====
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[[Image:johnes disease proliferative enteritis.jpg|thumb|right|150px|Johnes Disease (Courtesy of Bristol BioMed Image Archive)]]
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===Gross===
 
The infected host appears emaciated.
 
The infected host appears emaciated.
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Changes are milder in sheep and goats, than seen in cows, and is symptoms are often missed.
 
Changes are milder in sheep and goats, than seen in cows, and is symptoms are often missed.
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====Histologically====
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===Histologically===
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[[Image:johnes disease histological.jpg|thumb|right|150px|Histological appearance of Johnes disease (Courtesy of Bristol BioMed Image Archive)]]
      
There are many large macrophages (epithelioid macrophages) in mucosa, submucosa and lymph nodes.
 
There are many large macrophages (epithelioid macrophages) in mucosa, submucosa and lymph nodes.
Cmcory
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