Changes

==Description==  

==Description==  

Gastric neoplsia is uncommon and represents less than 1% of neoplasia in small animals. Aetiology is largely idiopathic though long term ingestion of dietary carcinogens may have some responsibility. Long term administration of nitrosamines may also cause carcinomas in dogs. In humans, ''Helicobacter pylori'' can induce gastric carcinomas and lymphomas. Its role in gastric tumours in dogs and cats has not yet been fully established though it is known to cause gastritis and ulceration. Belgian Shepherd dogs may have a genetic predisposition to gastric carcinomas. Cats with gastric lymphomas are usually FeLV positive.

Gastric [[Neoplasia - Pathology|neoplasia]] is uncommon and represents less than 1% of neoplasia in small animals. Aetiology is largely idiopathic though long term ingestion of dietary carcinogens may have some responsibility. In humans, ''Helicobacter pylori'' can induce gastric carcinomas and lymphomas. Its role in gastric tumours in dogs and cats has not yet been fully established though it is known to cause gastritis and ulceration. Belgian Shepherd dogs may have a genetic predisposition to gastric carcinomas. Cats with gastric lymphomas are usually FeLV positive.

 

 

Malignant tumours include:

Malignant tumours include:

Anterior abdominal pain may or may not be present

Anterior abdominal pain may or may not be present

Adenocarcinomas: frequently metastasise to the regional lymph nodes (gastroduodenal and splenic lymph nodes), also the liver and sometimes the lungs. They are also locally aggressive and can cause stomach wall perforation resulting in peritonitis. Other complications include:

Adenocarcinomas: frequently metastasise to the regional lymph nodes (gastroduodenal and splenic lymph nodes), also the liver and sometimes the lungs. They are also locally aggressive and can cause stomach wall perforation resulting in peritonitis. Other complications include pyloric outflow obstruction and ischaemic necrosis where tumour plugs develop in the surrounding vasculature.

* Pyloric outflow obstruction

* Ischaemic necrosis - where tumour plugs develop in the surrounding vasculature

Leiomyosarcomas: rarely metastasise.  

Leiomyosarcomas: rarely metastasise.  

Lymphoma: may be limited to the stomach, may affect lymph nodes and other abdominal organs or may be multicentric.  

Lymphoma: may be limited to the stomach, may affect lymph nodes and other abdominal organs or may be multicentric.  

Plasmacytoma: metastasis is frequently evident in local lymph nodes.

Plasmacytoma: metastasis is frequently evident in local lymph nodes.

===Haematology and biochemistry===

===Haematology and biochemistry===

A Regerative anaemia may be present due to gastric haemorrhage. Electrolyte disturabnces will be evident following vomiting and also elevated BUN and creatinine levels due to dehydration.

A Regerative anaemia may be present due to gastric haemorrhage. Electrolyte disturabnces will be evident following vomiting and also elevated BUN and creatinine levels due to dehydration.