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− | #REDIRECT[[Streptococcus equi subsp. equi]]
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| + | Caused by ''[[Streptococcus equi subsp. equi]]'' |
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| + | *Epidemiology |
| + | **[[Respiratory Bacterial Infections - Pathology#Strangles|Strangles]] is a highly infectious disease of horses caused by ''Streptococcus equi'' subsp. ''equi'' |
| + | **[[Respiratory Bacterial Infections - Pathology#In Horses|upper respiratory tract disease of horses]] with fever and abscessation of regional lymph nodes |
| + | **Cause rhinitis, [[Nasopharynx Inflammatory - Pathology|pharyngitis]], lymphadenitis and [[Muscles Inflammatory - Pathology#Abscesses|myositis]] |
| + | **Outbreaks in groups of young horses |
| + | **Transmitted via purulent exudate discharging from upper respiratory tract or from lymph nodes |
| + | **Chronic, carrier state can occur with bacteria im the guttural pouch |
| + | **A mild, atypical form can occur |
| + | **''S. equi'' shed for 4 weeks beyond clinical resolution |
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| + | *Clinical signs |
| + | **Incubation period 3 to 6 days |
| + | **Fever, depression, anorexia |
| + | **Purulent nasal discharge |
| + | **Swollen, painful regional lymph nodes, especially submandibular |
| + | **Abscessation and rupture of lymph nodes |
| + | **Guttural pouch empyema |
| + | **100% morbidity; 5% mortality |
| + | **Death can occur from pneumonia, breathing difficulties from swollen lymph nodes or [[Muscles Degenerative - Pathology#Ischaemia|purpura haemorrhagica]](an immune-mediated disease) |
| + | **Bastard strangle may occasionally occur, with abscessaation in many organs of the body |
| + | **''S. equi'' may be involved in [[Bacterial skin infections - Pathology#Systemic bacterial infections|cutaneous lesions]] |
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| + | *Diagnosis |
| + | **Clinical signs and history |
| + | **Mucoid colonies with beta-haemolysis |
| + | **Sugar fermentation allows differentiation of ''S. equi'' from ''S. zooepidemicus'' and ''S. equisimilis'' |
| + | **PCR to detect asymptomatic carriers |
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| + | *Treatment and control |
| + | **Penicillin administration to in-contact animals |
| + | **Isolation of affected animals |
| + | **Quarantne in-coming animals |
| + | **Avoid overcrowding and mixing different age groups |
| + | **Disinfection of equipment |
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| + | *Gross pathology |
| + | **Initial bilateral nasal discharge, serous becoming purulent |
| + | **Catarrhal conjunctivitis may be present |
| + | *Less frequently, complications can occur as follows : |
| + | **Purulent inflammation may extent to [[Guttural Pouches Inflammatory - Pathology|guttural pouches]] or [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|lungs]], [[Paranasal Sinuses Inflammatory - Pathology#Infectious causes of sinusitis|sinusitis]] |
| + | **Bacteraemia with metastatic abscesses - most often to the mesenteric and mediastinal lymph nodes, less frequently, other organs such as [[Liver - Anatomy & Physiology|liver]], kidney and brain can be involved - '''Bastard strangles''' |
| + | **Retropharyngeal abscesses can rupture onto the skin of neck or into the [[Guttural Pouches Inflammatory - Pathology|guttural pouch]] resulting in '''guttural pouch empyema or chondroid formation''' - carrier state |
| + | **[[Muscles Degenerative - Pathology#Ischaemia|'''Purpura haemorrhagica''']]: an acute vasculitis causing urticaria and extensive oedema of ventrum, head and distal limbs |
| + | **[[Larynx Degenerative - Pathology#Laryngeal hemiplegia|Laryngeal hemiplegia]] due to enlarged retropharyngeal lymph nodes |
| + | **Compression of cranial nerves |
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| + | *Interview with Professors Josh Slater and Ken Smith providing an interesting insight into the pathogenesis, prevalence and possible prevention of ''Streptococcus equi'' infections in horses - listen to [http://www.rvc.ac.uk/Review/Podcasts/RVC_Podcast_12.m4a Strangles podcast] |
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| + | [[Category:Respiratory_Bacterial_Infections]] |
| + | [[Category:Respiratory_Disorders_-_Horse]] |
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| + | [[Category:To_Do_-_Respiratory]] |