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Contagious Bovine Pleuropneumonia (view source)
Revision as of 11:31, 2 August 2010
, 11:31, 2 August 2010no edit summary
[[Image:Contagious bovine pleuropneumonia.jpg|right|thumb|100px|<small><center>Contagious bovine pleuropneumonia (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
[[Image:Contagious bovine pleuropneumonia.jpg|right|thumb|100px|<small><center>Contagious bovine pleuropneumonia (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
*Aerosol transmission by close contact with clinically or subclinically affected animals
*Severity depends on strain and host susceptibility
*Slow spread of infection
*50% morbidity; mortality rate high in severe outbreaks
*Large colony type causes pleuropneumonia, mastitis, septicaemia and polyarthritis
*Clinical signs
**Acute onset fever, anorexia, depression, lowered milk yield, hyperpnoea, coughing and a mucopurulent nasal discharge
**Dyspnoea occurs with abducted elbows and extended necks and an expiratory grunt
**Can be fatal within 1-3 weeks
**Calves may suffer from [[Joints Inflammatory - Pathology#In Cattle|arthritis]], synovitis and endocarditis
*Gross pathology
**Marbled appearance to lungs with consolidated grey and red lobules separated by emphysematous areas
**Serofibrinous pleural fluid
**Necrotic foci surrounded by fibrous capsules in chronic cases act as source of infection
*Diagnosis
**Clinical signs and post-mortem appearance
**PCR on pleural fluid, lung tissue, regional lymph nodes or bronchoalveolar lavage fluid
**Fluorescent antibody test
**Serological tests such as serum agglutination, haemagglutination, complement fixation, ELISA
*Treatment and control
**Slaughter of affected cattle in counries where the disease is exotic
**Movement restrictions, quaranteen and slaughter of carrier animals in endemic countries
*''M. mycoides'' subsp. 'mycoides'' causes septicaemia, pleuropneumonia, arthritis and mastitis in goats
**Vaccination in endemic regions
*Caused by [[Mycoplasma mycoides subsp. mycoides|''Mycoplasma mycoides'']], small colony variant
*Caused by [[Mycoplasma mycoides subsp. mycoides|''Mycoplasma mycoides'']], small colony variant
*Causes a fibrinonecrotic [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]] and [[Pleural Cavity & Membranes Inflammatory - Pathology|fibrinous pleuritis]]
*Causes a fibrinonecrotic [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]] and [[Pleural Cavity & Membranes Inflammatory - Pathology|fibrinous pleuritis]]
*Also affects caudodorsal areas
*Also affects caudodorsal areas
*[[Lungs Inflammatory - Pathology#Bronchopneumonia|Bronchopneumonia]] -> [[Lungs Inflammatory - Pathology#Lobar pneumonia|lobar pneumonia]]
*[[Lungs Inflammatory - Pathology#Bronchopneumonia|Bronchopneumonia]] -> [[Lungs Inflammatory - Pathology#Lobar pneumonia|lobar pneumonia]]
*Sequestra are common
*Sequestra are common
*NB: similarity to pneumonic pasteurellosis but CBPP has more pronounced marbled effect
*NB: similarity to pneumonic pasteurellosis but CBPP has more pronounced marbled effect