Changes

* The fibroblasts tend to align themselves roughly horizontal to the surface, but the endothelium is perpendicular to the surface.

* The fibroblasts tend to align themselves roughly horizontal to the surface, but the endothelium is perpendicular to the surface.

** The upper vessels form loops near to the surface.

** The upper vessels form loops near to the surface.

*** Gives the gross appearance of red granules - this is [[Chronic Inflammation - Pathology#Granulation Tissue|granulation tissue]].

*** Gives the gross appearance of red granules - this is [[Granulation Tissue|granulation tissue]].

* Well-formed granulation tissue tends to be fairly resistant to surface infection; however, it is rather delicated and so susceptible to trauma and subsequent introduction of infection.

* Well-formed granulation tissue tends to be fairly resistant to surface infection; however, it is rather delicated and so susceptible to trauma and subsequent introduction of infection.

** Infection is therefore a common complication in the early stages of healing.

** Infection is therefore a common complication in the early stages of healing.